中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共63条,第1-10条 帮助

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Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:  
Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin
  |  收藏  |  浏览/下载:7/0  |  提交时间:2024/03/06
Rhodium-Catalyzed Diastereoselective C-H Activation/[4+2] Annulation of α,β-Unsaturated Amides with Bicyclic Alkenes 期刊论文  OAI收割
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 2, 页码: 483-487
作者:  
Wang, Yan;  Shi, Sijia;  Zhang, Wei;  Nian, Yong;  Wu, Xiaowei
  |  收藏  |  浏览/下载:15/0  |  提交时间:2024/02/27
Targeting NMDA Receptors in Emotional Disorders: Their Role in Neuroprotection 期刊论文  OAI收割
BRAIN SCIENCES, 2022, 卷号: 12, 期号: 10, 页码: 17
作者:  
Wang, Siqi;  Bian, Lihua;  Yin, Yi;  Guo, Jianyou
  |  收藏  |  浏览/下载:21/0  |  提交时间:2022/11/27
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:  
Li, Xiaokang;  Li, Jinwen;  Huang, Yunyuan;  Gong, Qi;  Fu, Yan
  |  收藏  |  浏览/下载:31/0  |  提交时间:2022/06/15
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  
Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei
  |  收藏  |  浏览/下载:26/0  |  提交时间:2022/01/04
Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文  OAI收割
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:  
Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin
  |  收藏  |  浏览/下载:30/0  |  提交时间:2021/11/01
Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor 期刊论文  OAI收割
ELIFE, 2021, 卷号: 10, 页码: 20
作者:  
Zhao, Fenghui;  Zhang, Chao;  Zhou, Qingtong;  Hang, Kaini;  Zou, Xinyu
  |  收藏  |  浏览/下载:32/0  |  提交时间:2021/08/17
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia 期刊论文  OAI收割
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:  
Wang, Yu;  He, Yang;  Yang, Feipu;  Abame, Melkamu Alemu;  Wu, Chunhui
  |  收藏  |  浏览/下载:23/0  |  提交时间:2021/11/04
Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations 期刊论文  OAI收割
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989
作者:  
An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Huanxiang;  Yao, Xiaojun
  |  收藏  |  浏览/下载:16/0  |  提交时间:2021/12/08
Characterization of the GABAergic system in Asian clam Corbicula fluminea: Phylogenetic analysis, tissue distribution, and response to the aquatic contaminant carbamazepine 期刊论文  OAI收割
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2021, 卷号: 239
作者:  
Chen, Huihui;  Gu, Xiaohong;  Zeng, Qingfei;  Mao, Zhigang;  Martyniuk, Christopher J.
  |  收藏  |  浏览/下载:12/0  |  提交时间:2022/03/10