机构

• 上海药物研究所 [43]
• 生态环境研究中心 [5]
• 昆明植物研究所 [4]
• 大连化学物理研究所 [3]
• 生物物理研究所 [2]
• 长春应用化学研究所 [2]
• 更多

采集方式

• OAI收割 [63]
• iSwitch采集 [1]

内容类型

• 期刊论文 [61]
• 学位论文 [3]

发表日期

• 2024 [4]
• 2023 [6]
• 2021 [4]
• 2020 [4]
• 2019 [3]
• 2018 [5]
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学科主题

• Pharmacolo... [6]
• Neuroscien... [4]
• 环境科学::环境化学 [3]
• Chemistry [2]
• Analytical... [1]
• Biochemica... [1]
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浏览/检索结果: 共64条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16 作者:  Zheng, Jiefang;  Zhou, Liping;  Gong, Xudong;  Yang, Feipu;  Cheng, Jiaxin   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/08/22 Triple reuptake inhibitors  5-HT 1A R agonists  Antidepressants  Multimodal serotonergic compounds   Structural basis for activation of somatostatin receptor 5 by cyclic neuropeptide agonists 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 26, 页码: 10 作者:  Li, Jingru;  You, Chongzhao;  Li, Yang;  Li, Changyao;  Fan, Wenjia   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/08/22 SSTR5  peptide agonists  agonist selectivity  receptor activation   A new mechanism of thyroid hormone receptor β agonists ameliorating nonalcoholic steatohepatitis by inhibiting intestinal lipid absorption via remodeling bile acid profiles 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15 作者:  Sun, Kai;  Zhu, Nan-lin;  Huang, Su-ling;  Qu, Hui;  Gu, Yi-pei   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/07/12 nonalcoholic steatohepatitis  THR beta agonists  resmetirom  bile acids composition  intestinal lipid absorption   Update on the development of TGR5 agonists for human diseases 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 271, 页码: 20 作者:  Jin, Wangrui;  Zheng, Mingyue;  Chen, Yihua;  Xiong, Hai   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/07/12 Bile acids  TGR5  T2DM  Gut-targeted TGR5 agonists   Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17 作者:  Zhu, Yueyue;  Liu, Bo;  Chen, Zonglong;  Wang, Xianyang   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/12/08 Toll -like receptor 2/6 agonists  PamCS  Structure-activity relationship  Lipopeptide  Immunostimulants   Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 17 作者:  Zhang, Ranran;  Wang, Pengyu;  Wei, Bingyan;  Chen, Liang;  Song, Xiaomin   |  收藏  |  浏览/下载：33/0  |  提交时间：2023/10/17 ClpP agonists  Structure-activity relationship  Mitochondrial respiratory chain  Antileukemic therapy   Structure-Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 9 作者:  Shen, Chang;  Xu, Peijia;  Zhang, Changfa;  Su, Zhaoming;  Shan, Bin   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/10/17 cGAS-STING signaling pathway  STING agonists  antitumor immunity  anti-infection immunity   Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213 作者:  Sun, Nannan;  Yu, Mingcheng   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/27 ROR?t agonists  Carbazole carboxamide  Agonistic activity  Metabolic stability  Co-crystallization  Molecular docking   Advances in Medicinal Chemistry of Estrogen-related Receptor Alpha (ERRa) Inverse Agonists 期刊论文  OAI收割 CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 20, 页码: 1952-1963 作者:  Zhang, Haibin;  Du, Yongli;  Zheng, Yong;  Lv, Huiting;  Yan, Zhijia   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 ERRalpha  ERRalpha inverse agonists  Breast cancer  TNBC  Signaling pathways  Inverse agonistic activity   Small-Molecule Drugs in Immunotherapy 期刊论文  OAI收割 MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359 作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili   |  收藏  |  浏览/下载：166/0  |  提交时间：2024/07/25 Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN