机构

• 上海药物研究所 [6]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2021 [1]
• 2020 [1]
• 2019 [1]
• 2018 [1]
• 2015 [1]
• 2013 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269 作者:  Yin, Jianpeng;  Zhan, Desheng;  Ma, Hui;  Liu, Huanan;  Yu, Lifang   |  收藏  |  浏览/下载：25/0  |  提交时间：2021/12/16 YLF466D  AMPK activator  glucose metabolism  lipid metabolism  MIRI  domino reaction  C-H activation   AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong   |  收藏  |  浏览/下载：36/0  |  提交时间：2020/12/24 adenosine 5 '-monophosphate-activated protein kinase  AMPK activator  C24  liver  triglycerides  cholesterol  VLDL  hypolipidemic drug  metabolic syndrome   Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176 作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping   |  收藏  |  浏览/下载：68/0  |  提交时间：2019/07/29 Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator   Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632 作者:  Zhang, Mei;  Xie, Zhi-fu;  Zhang, Run-tao;  Chen, Da-kai;  Gu, Min   |  收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 non-alcoholic fatty liver disease  AMP-activated protein kinase  AMPK activator  homogeneous time-resolved fluorescence  metabolic disorders  ob/ob mice   Development of a Novel Phosphorylated AMPK Protection Assay for High-Throughput Screening Using TR-FRET Assay 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR SCREENING, 2015, 卷号: 20, 期号: 7, 页码: 906-912 作者:  Xu, Yazhou;  Wang, Yunjie;  Xu, Yuan;  Li, Jia;  Liao, Hong   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 AMPK  phosphatase PP2A  high-throughput screening  TR-FRET  AMPK activator   Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice 期刊论文  OAI收割 TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 273, 期号: 2, 页码: 325-334 作者:  Li, Yuan-Yuan;  Yu, Li-Fang;  Zhang, Li-Na;  Qiu, Bei-Ying;  Su, Ming-Bo   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 AMPK  Activator  Allosteric  Small-molecule  Orally effective  Metabolic syndrome   Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 4, 期号: 5, 页码: 475-480 作者:  Yu, Li-Fang;  Li, Yuan-Yuan;  Su, Ming-Bo;  Zhang, Mei;  Zhang, Wei   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 AMPK activator  alkene oxindole  DIO mouse model  insulin sensitivity  diabetes