机构

• 上海药物研究所 [26]
• 昆明植物研究所 [9]
• 过程工程研究所 [7]
• 大连化学物理研究所 [4]
• 化学研究所 [2]
• 中国科学院大学 [1]
• 更多

采集方式

• OAI收割 [49]
• iSwitch采集 [1]

内容类型

• 期刊论文 [48]
• 学位论文 [2]

发表日期

• 2021 [1]
• 2020 [1]
• 2019 [1]
• 2018 [6]
• 2017 [1]
• 2016 [3]
• 更多

学科主题

• Biochemist... [1]
• Biophysics [1]
• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共50条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPAR alpha agonists by in silico studies and biochemical evaluation 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 16 作者:  Li, Yue;  Lv, Mengjia;  Shen, Meiling;  Gu, Xi;  Zhang, Li   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation   Review of Voltage-gated Calcium Channel alpha 2 delta Subunit Ligands for the Treatment of Chronic Neuropathic Pain and Insight into Structure-activity Relationship (SAR) by Pharmacophore Modeling 期刊论文  OAI收割 CURRENT MEDICINAL CHEMISTRY, 2022, 卷号: 29, 期号: 30, 页码: 5097-5112 作者:  Chen, Yuting;  Wu, Qingqing;  Jin, Zhengsheng;  Qin, Yanlan;  Meng, Fancui   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/11/11 Voltage-gated calcium channel  alpha 2 delta subunit  neuropathic pain  structure-activity relationship (SAR)  pharmacophore modeling  gabapentinoids   Discovery of potentially biased agonists of mu-opioid receptor (MOR) through molecular docking, pharmacophore modeling, and MD simulation 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2021, 卷号: 90, 页码: 107405 作者:  Jiang,Xuan;  Li,Shuxiang;  Zhang,Hongbin;  Wang,Liang-Liang   |  收藏  |  浏览/下载：13/0  |  提交时间：2022/04/02 mu-Opioid receptors (MOR)  Biased ligands  Molecular docking  Hip-hop pharmacophore  MD simulation   Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds 期刊论文  OAI收割 FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2020, 卷号: 10, 页码: 12 作者:  Liu, Congshan;  Yin, Jianhai;  Yao, Jiaqing;  Xu, Zhijian;  Tao, Yi   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 echinococcosis  Echinococcus multilocularis  pharmacophore modeling  virtual screenings  in vitro drug screen  cytotoxicity  E  multilocularis-infected mice  pharmacokinetics analysis   Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176 作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping   |  收藏  |  浏览/下载：63/0  |  提交时间：2019/07/29 Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator   Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60 作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying   |  收藏  |  浏览/下载：29/0  |  提交时间：2018/11/12 Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations   Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文  OAI收割 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915 作者:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong   |  收藏  |  浏览/下载：50/0  |  提交时间：2018/11/06 Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation   Computer-Aided Drug Design in Epigenetics 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2018, 卷号: 6 作者:  Lu, Wenchao;  Zhang, Rukang;  Jiang, Hao;  Zhang, Huimin;  Luo, Cheng   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 drug discovery  epigenetics  small-molecule inhibitor  computer-aided drug design  virtual screening   Pharmacophore modeling, molecular docking and molecular dynamics studies on natural products database to discover novel skeleton as non-puricie xanthine oxidase inhibitors 期刊论文  OAI收割 PLASTID GENOME EVOLUTION, 2018, 卷号: 85, 页码: 293-313 作者:  Peng, Jiale;  Li, Yaping;  Zhou, Yeheng;  Zhang, Li;  Liu, Xingyong   |  收藏  |  浏览/下载：24/0  |  提交时间：2018/12/27 Pharmacophore modeling, molecular docking and molecular dynamics studies on natural products database to discover novel skeleton as non-puricie xanthine oxidase inhibitors 期刊论文  OAI收割 JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2018, 卷号: 38, 期号: 3, 页码: 246-255 作者:  Peng, Jiale;  Li, Yaping;  Zhou, Yeheng;  Zhang, Li;  Liu, Xingyong   |  收藏  |  浏览/下载：30/0  |  提交时间：2019/03/29