中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2018 [1]
2017 [1]
2016 [1]
2015 [1]
2014 [1]
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Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK)
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:
Gu, Zhanni
;
Wu, Lingyan
;
Duan, Yanan
;
Wang, Jiang
;
Zhou, Shengbin
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
Adenosine 5 '-monophosphate-activated protein kinase
AMPK activators
Berberine
Tetrahydroberberine
T2DM
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:
Zhou, Shengbin
;
Duan, Yanan
;
Wang, Jiang
;
Zhang, Jin
;
Sun, Haifeng
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Tetrahydroberberine
4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines
Mitochondrial respiration
AMPK indirect activators
db/db mice
Discovery, synthesis, and structure-activity relationships of 20S-dammar-24-en-2 alpha,3 beta,12 beta,20-tetrol (GP) derivatives as a new class of AMPK alpha 2 beta 1 gamma 1 activators
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2688-2696
作者:
Dong, Chenhuan
;
Xie, Zhifu
;
Yu, Yanyan
;
Li, Jia
;
Liu, Junhua
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Gynostemma yixingense
Dammarane-type
AMPK
AMPK heterotrimer alpha 2 beta 1 gamma 1
Activators
Structure-activity relationships
Recent research progress in small molecule AMPK direct activators
期刊论文
OAI收割
Journal of China Pharmaceutical University, 2015, 卷号: 46, 期号: 4, 页码: 406-415
作者:
Wei Qiangqiang
;
Duan Wenhu
;
Zhou Jinpei
;
Zhang Huibin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
AMP-activated protein kinase
AMPK direct activators
structure-activity relationship
type 2 diabetes
new target
advances
Discovery, synthesis, and structure activity relationships of 20(S)-protopanaxadiol (PPD) derivatives as a novel class of AMPK alpha 2 beta 1 gamma 1 activators
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 79, 页码: 340-349
作者:
Liu, Junhua
;
Chen, Dakai
;
Liu, Peng
;
He, Mengna
;
Li, Jia
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
20(S)-Protopanoxadiol
AMPK
AMPK heterotrimer alpha 2 beta 1 gamma 1
Activators
Structure-activity relationship