机构

• 上海药物研究所 [19]
• 上海神经科学研究所 [13]
• 金属研究所 [7]
• 心理研究所 [2]
• 中国科学院大学 [2]
• 长春应用化学研究所 [2]
• 更多

采集方式

• OAI收割 [51]
• iSwitch采集 [3]

内容类型

• 期刊论文 [54]

发表日期

• 2025 [4]
• 2021 [1]
• 2018 [1]
• 2017 [2]
• 2016 [2]
• 2015 [1]
• 更多

学科主题

• Neuroscie... [10]
• Biochemist... [3]
• Cell Biolo... [1]
• Life Scien... [1]
• Multidisci... [1]
• Pharmacolo... [1]
• 更多

筛选

浏览/检索结果: 共54条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13 作者:  Li, Kun;  Zeng, Yue;  Xiong, Yi-da;  Wu, Hao-chen;  Fang, Sui   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/08/20 drug-target affinity prediction  virtual screening  contrastive learning  graph neural network  N-methyl-D-aspartate (NMDA) receptors  GluN3A subunit.   Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8 作者:     |  收藏  |  浏览/下载：13/0  |  提交时间：2025/07/25 N-methyl-D-aspartate receptors  GluN1/GluN3A  ligand-based virtual screening  scaffold hopping  deep learning  GeminiMol   Multi-gene metabolic engineering of Pichia pastoris to synthesize ectoine 期刊论文  OAI收割 JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2025, 卷号: 139, 期号: 5, 页码: 347-353 作者:  Zhang, Shuai;  Cheng, Bingjie;  Liao, Qing;  Huang, Xuewu;  Mi, Mengjiao   |  收藏  |  浏览/下载：18/0  |  提交时间：2025/05/27 Pichia pastoris  Ectoine  ectABC  Metabolic engineering  L-Aspartate-beta-semialdehyde   An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9 作者:  Wang, Ze-chen;  Zeng, Yue;  Sun, Jin-yuan;  Chen, Xue-qin;  Wu, Hao-chen   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/04/24 deep learning  scoring function  GluN1/GluN3A receptor  N-methyl-D-aspartate (NMDA) receptor  virtual screening  drug discovery   Design, Synthesis and Bioactivity of NYX-2925 L-Proline Derivatives as N-Methyl-D-aspartate (NMDA) Receptor Partial Agonists 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 4, 页码: 1247-1263 作者:  Wu Youjin;  Jin Zhengsheng;  Liu Yongjia;  Huang Wenqian;  Zhao Guilong   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/08/22 N-methyl-D-aspartate (NMDA) receptor  partial agonist  NYX-2925  synthesis  bioactivity   Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 13 作者:  Zeng, Yue;  Zheng, Yueming;  Zhang, Tongtong;  Ye, Fei;  Zhan, Li   |  收藏  |  浏览/下载：54/0  |  提交时间：2022/08/16 N-methyl-D-aspartate (NMDA) receptors  GluN3 subunits  WZB117  allosteric modulator  ion channels  drug discovery   Comprehensive B-Cell Immune Repertoire Analysis of Anti-NMDAR Encephalitis and Anti-LGI1 Encephalitis 期刊论文  OAI收割 FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12, 页码: 12 作者:  Feng, Jingjing;  Fan, Siyuan;  Sun, Yinwei;  Ren, Haitao;  Guan, Hongzhi   |  收藏  |  浏览/下载：43/0  |  提交时间：2021/11/12 anti-N-methyl-D-aspartate receptor encephalitis  anti-leucine-rich glioma-inactivated 1 encephalitis  B-cell immune repertoire  common clones  adaptive immune responses   GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1 期刊论文  OAI收割 FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11 作者:  Zhou, Dongsheng;  Lv, Dan;  Wang, Zhen;  Zhang, Yanhua;  Chen, Zhongming   |  收藏  |  浏览/下载：96/0  |  提交时间：2019/01/08 GLYX-13  disrupted-in-schizophrenia 1  N-methyl-D-aspartate receptor  N-methyl D-aspartate receptor subtype 2B  schizophrenia   Incorporation of Dihydroartemisinin into Memantine Through a Propriate Spacer to Make Hybrid with Enhanced Effects to Protect PC12 Cells from Corticosterone-caused Impairments 期刊论文  OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 4, 页码: 611-622 作者:  Zhang Lei;  Zhou Fan;  Zhang Laitao;  Peng Lizhi;  Guo Cuiping   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Artemisinin  Memantine  Neuroprotection  N-Methyl-D-aspartate(NMDA) receptor  Depression   Liver Protective and Reactive Oxygen Species Scavenging Effects of Emodin in Lipopolysaccharide/Bacillus Calmette Guerin-injured Mice by Optical Molecular Imaging 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2017, 卷号: 13, 期号: 2, 页码: 175-182 作者:  Li, Na;  Wang, Jia-Bo;  Zhao, Yan-Ling;  Zhang, Lin;  Ma, Xi-Bo   |  收藏  |  浏览/下载：30/0  |  提交时间：2017/05/05 Emodin  Hepatoprotection  Reactive Oxygen Species  Molecular Imaging  Lipopolysaccharide  Nuclear Factor Kappa b  Anti-oxidation  Alanine Aminotransferase  Aspartate Transaminase