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Synthesis, photophysical properties and fluorescent application of novel [1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one derivatives
期刊论文
OAI收割
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2025, 卷号: 464, 页码: 11
作者:
Gan, Suya
;
Gao, Li-Xin
;
Cao, Zitong
;
Zhang, Chun
;
Fu, Yiqiu
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2025/04/01
[1
4]triazolo[1
5-a]pyrimidin-7(4H)-one
derivatives
Fluorescence properties
Fe 3+ions
Glabridin as a selective Kv2.1 inhibitor ameliorates DPN pathology by disrupting the Aβ/Kv2.1/JNK/NF-κB/NLRP3/p-Tau pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 17
作者:
Xu, Jia-wen
;
Ma, Lin
;
Xiang, Yu
;
Dai, Meng-qing
;
Li, Qiu-hui
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/05/27
diabetic peripheral neuropathy
glabridin
Kv2.1
dorsal root ganglia
Schwann cells
A beta/Kv2.1/NLRP3/p-Tau axis
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
CXCR2 modulates chronic pain comorbid depression in mice by regulating adult neurogenesis in the ventral dentate gyrus
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13
作者:
Li, Xiao-jie
;
Wu, Shuo
;
Liu, Zi-han
;
Liu, An-an
;
Peng, Hui-sheng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/04/01
chronic pain comorbid depression
adult neurogenesis
dentate gyrus
CXCR2
Wnt3a/beta-catenin pathway
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:
Ren, Xiaojing
;
Teng, Yunfei
;
Xie, Kunxin
;
He, Xiao
;
Chen, Gang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/04/01
REG3A
Pancreatic ductal adenocarcinoma
Peritumoral acinar cell
Epidermal growth factor receptor (EGFR)
Paracrine
Quantifying the Evolution of Extreme Drought Under Climate Change and Its Impacts on Vegetation Productivity Over the Hai River Basin of China
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF CLIMATOLOGY, 2024, 卷号: N/A
作者:
Yao, Tingting
;
Liu, Suxia
;
Hu, Shi
;
Mo, Xingguo
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/01/17
climate trends
extreme droughts
gross primary productivity (GPP)
Inter-Sectoral Impact Model Intercomparison Project-3a (ISIMIP3a)
Run theory
Standardised Precipitation Evapotranspiration Index (SPEI)
An overview of the functions and mechanisms of APOBEC3A in tumorigenesis
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4637-4648
作者:
Yang, Yuqi
;
Liu, Nan
;
Gong, Likun
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/01/06
Tumor-associated viruses
Tumor microenvironment
APOBEC3A
Deaminase
Mutation
DNA damage
Tumorigenesis
Tumor-associated viruses
Macrophage
Tumor microenvironment
Activin A plays an essential role in migration and proliferation of hepatic stellate cells via Smad3 and calcium signaling
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2024, 卷号: 14
作者:
Zhang, Wei
;
Zhu, Linjing
;
Fang, Fang
;
Zhang, Fenglin
;
Wang, Runnan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/11/20
Hepatic stellate cells
Proliferation
Migration
Activin A
Smad3
Calcium signaling
The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13
作者:
Cheng, Jiaxin
;
Wu, Chunhui
;
Wang, Yu
;
Wang, Zhen
;
He, Yang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/24
TPN672MA
5-HT 1A receptor agonist
D 2 /D 3 receptor partial agonist
5-HT 2A receptor antagonist
Antidepressant-like
Mechanism
The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 716, 页码: 12
作者:
Xuan, Yi-Fei
;
Lu, Shan
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/07/12
MAT2A inhibitor
METTL3 inhibitor
m6A
Combination therapy
NSCLC