中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
昆明植物研究所 [2]
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OAI收割 [8]
内容类型
期刊论文 [8]
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2022 [1]
2019 [1]
2018 [1]
2016 [1]
2014 [1]
2013 [1]
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Chemistry [2]
Pharmacolo... [2]
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Simultaneous determination of almonertinib and its active metabolite HAS-719 in human plasma by LC-MS/MS: Evaluation of pharmacokinetic interactions
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2022, 卷号: 1197, 页码: 7
作者:
Liu, Lu
;
Yang, Le
;
Li, Wei
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/08/16
Almonertinib
LC -MS
MS
Active metabolite (HAS-719)
Pharmacokinetic drug-drug interaction
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160
作者:
Li, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
  |  
收藏
  |  
浏览/下载:119/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 149, 页码: 394-402
作者:
Liu, Cai
;
Lu, Youming
;
Sun, Hongbin
;
Yang, Jin
;
Liu, Yongqiang
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
Active metabolite
LC-MS/MS
Human plasma
P2Y(12) inhibitor
Hypouricaemic action of mangiferin results from metabolite norathyriol via inhibiting xanthine oxidase activity
期刊论文
OAI收割
PHARMACEUTICAL BIOLOGY, 2016, 卷号: 54, 期号: 9, 页码: 1680-1686
作者:
Niu, Yanfen
;
Liu, Jia
;
Liu, Hai-Yang
;
Gao, Li-Hui
;
Feng, Guo-Hua
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2017/01/05
Active metabolite
hyperuricaemia
structure-activity relationship
uric acid production
Mangiferin and its aglycone, norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase
期刊论文
OAI收割
PHARMACEUTICAL BIOLOGY, 2014, 卷号: 52, 期号: 1, 页码: 68-73
作者:
Wang, Fang
;
Yan, Juming
;
Niu, Yanfen
;
Li, Yan
;
Lin, Hua
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2014/04/09
Active metabolite
AMPK
insulin resistance
L6 muscle cells
norathyriol
Simultaneous determination of erdosteine and its active metabolite in human plasma by liquid chromatography-tandem mass spectrometry with pre-column derivatization
期刊论文
OAI收割
Acta Pharmaceutica Sinica, 2013, 卷号: 48, 期号: 3, 页码: 395-400
作者:
Jin Jing
;
Chen Xiaoyan
;
Zhang Yifan
;
Ma Zhiyu
;
Zhong Dafang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
LC-MS/MS
erdosteine
pharmacokinetics
active metabolite