中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2021 [1]
2019 [1]
2018 [2]
2016 [1]
2008 [1]
学科主题
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Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:
Gao, Feng
;
Chen, Xiaoxu
;
Lu, Junyan
;
Hu, Shulei
;
Xu, Hui
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Ceramide analogs
AKT inhibitor
MK2206
Colon cancer
Combination therapy
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:
Zhan, Wenhu
;
Che, Jinxin
;
Xu, Lei
;
Wu, Yizhe
;
Hu, Xiaobei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Pyrazole-thiophene derivatives
Akt inhibitor
Antitumor
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:
Basnet, Rajesh
;
Gong, Grace Qun
;
Li, Chenyao
;
Wang, Ming-Wei
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
SGK
AKT
PI3K
Cancer
Signalling: Kinase
Inhibitor
serumandglucocorticoidinducibleproteinkinasessgksapotentialtargetforcancerintervention
期刊论文
OAI收割
actapharmaceuticasinicab, 2018, 卷号: 000, 期号: 005, 页码: 767
作者:
Basnet Rajesh
;
Gong Grace Qun
;
Li Chenyao
;
Wang Mingwei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
SGK
AKT
PI3K
Cancer
Signalling
Kinase
Inhibitor
Design, synthesis and biological evaluation of pyrazol-furan carboxamide analogues as novel Akt kinase inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 117, 页码: 47-58
作者:
Zhan, Wenhu
;
Xu, Lei
;
Dong, Xiaowu
;
Dong, Jun
;
Yi, Xiao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Akt1 inhibitor
Synthesis
Cytotoxicity
Molecular docking
Cancer
Antitumor activity of a new N-substituted thiourea derivative, an EGFR signaling-targeted inhibitor against a panel of human lung cancer cell lines
期刊论文
OAI收割
CHEMOTHERAPY, 2008, 卷号: 54, 期号: 6, 页码: 463-474
作者:
Xiong, Xishan
;
Liu, Hong
;
Fu, Lili
;
Li, Lin
;
Li, Jian
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
EGFR
tyrosine kinase inhibitor
non-small-cell lung cancer
IC50
Erk1/2
AKT