机构

• 上海药物研究所 [8]
• 昆明植物研究所 [6]
• 西双版纳热带植物园 [1]
• 武汉物理与数学研究所 [1]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2025 [1]
• 2023 [1]
• 2021 [1]
• 2020 [1]
• 2019 [2]
• 2018 [2]
• 更多

学科主题

• Biochemist... [1]
• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan;  Yang, Bowen   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493 作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/07/22 Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION   Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811 作者:  Yuan,Hai-Lian;  Zhao,Yun-Li   |  收藏  |  浏览/下载：58/0  |  提交时间：2022/04/02 Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators   Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 293-302 作者:  Wang, Jin-tao;  Zheng, Yue-ming;  Chen, Yue-ting;  Gu, Min;  Gao, Zhao-bing   |  收藏  |  浏览/下载：57/0  |  提交时间：2020/07/01 Nav1  7 sodium channel  aryl sulfonamide  maprotiline  compound 10o  electrophysiology  acetic acid-induced visceral pain  analgesic activity   Seven new veratramine-type alkaloids with potent analgesic effect from Veratrum taliense 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 244, 页码: 7 作者:  Li, Qiong;  Zhao, Yun-Li;  Long, Cheng-Bo;  Zhu, Pei-Feng;  Liu, Ya-Ping   |  收藏  |  浏览/下载：113/0  |  提交时间：2019/11/07 V. taliense  Veratrum  Liliaceae  Veratramine-type alkaloids  Analgesic activity   An overview of grayanane diterpenoids and their biological activities from the Ericaceae family in the last seven years 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 400-416 作者:  Li, Chun-Huan;  Zhang, Jia-Yao;  Zhang, Xiu-Yun;  Li, Sheng-Hong;  Gao, Jin-Ming   |  收藏  |  浏览/下载：126/0  |  提交时间：2019/04/15 Grayanane diterpenoids  Ericaceae  Bioactivities  Analgesic activity  Anti-inflammatory activity  PTP1B inhibitory activity  Structure-activity relationship   Identification of Potential Biomarkers from Aconitum carmichaelii, a Traditional Chinese Medicine, Using a Metabolomic Approach 期刊论文  OAI收割 PLANTA MEDICA, 2018, 卷号: 84, 期号: 6-7, 页码: 434-441 作者:  Zhao, Dake;  Shi, Yana;  Zhu, Xinyan;  Liu, Li;  Ji, Pengzhang   |  收藏  |  浏览/下载：88/0  |  提交时间：2018/07/02 Aconitum  Aconitum Carmichaelii  Ranunculaceae  Aconitum Alkaloids  Diterpene Alkaloids  Analgesic Activity  Acute Toxicity  Traditional Chinese Medicine  Tcm   Identification of Potential Biomarkers from Aconitum carmichaelii, a Traditional Chinese Medicine, Using a Metabolomic Approach 期刊论文  OAI收割 PLANTA MEDICA, 2018, 卷号: 84, 期号: 43258, 页码: 434-441 作者:  Zhao, Dake;  Shi, Yana;  Zhu, Xinyan;  Liu, Li;  Ji, Pengzhang   |  收藏  |  浏览/下载：57/0  |  提交时间：2018/06/07 Aconitum  Aconitum Carmichaelii  Ranunculaceae  Aconitum Alkaloids  Diterpene Alkaloids  Analgesic Activity  Acute Toxicity  Traditional Chinese Medicine  Tcm   Im10A, a short conopeptide isolated from Conus imperialis and possesses two highly concentrated disulfide bridges and analgesic activity 期刊论文  OAI收割 PEPTIDES, 2016, 卷号: 81, 页码: 15-20 作者:  Yu, Shuo;  Du, Tianpeng;  Liu, Zhuguo;  Wu, Qiaoling;  Feng, Guixue 收藏  |  浏览/下载：54/0  |  提交时间：2016/07/12 Conopeptide  Im10A  Isolation  Synthesis  NMR structure  Analgesic activity   Four new C-18-diterpenoid alkaloids with analgesic activity from Aconitum weixiense 期刊论文  OAI收割 FITOTERAPIA, 2013, 卷号: 91, 页码: 280-283 作者:  Zhao, Da-Ke;  Ai, Hong-Lian;  Zi, Shu-Hui;  Zhang, Li-Mei;  Yang, Sheng-Chao 收藏  |  浏览/下载：54/0  |  提交时间：2014/01/13 Diterpenoid alkaloids  Weisaconitines A-D  Analgesic activity  Aconitum weixiense  Ranunculaceae