中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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昆明植物研究所 [55]
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Jatrophane and ingenane diterpenoids with anti-inflammatory activity from
Euphorbia esula
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 13
作者:
Li, Yu-Peng
;
Li, Ying
;
Gao, Wen-Jing
;
Fang, Chu-Hong
;
Lv, Ming-Jun
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2025/04/01
Euphorbia esula L.
Euphorbiaceae
Diterpenoid
Anti-inflammatory
NF-kappa B/MAPK
Nrf2/HO-1
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3-
d
]pyrimidin-7-one-based SOS1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9
作者:
Wang, Kun
;
Zhou, Zehui
;
Ma, Xinyi
;
Xu, Jiahang
;
Xu, Wangyang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/07/12
SOS1
KRAS mutation
PROTAC
Anti-cancer activity
Autoantibodies against eukaryotic translation elongation factor 1 delta in two patients with autoimmune cerebellar ataxia
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 14, 页码: 8
作者:
Guo, Liyuan
;
Ren, Haitao
;
Fan, Siyuan
;
Chao, Xingchen
;
Liu, Mange
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/04
autoimmune
cerebellar ataxia
biomarker
novel autoantibody
anti-EEF1D antibody
Benzothiozinone derivatives with anti-tubercular Activity-Further side chain investigation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 11
作者:
Wu, Xiaomei
;
Wang, Wenxin
;
Stelitano, Giovanni
;
Riabova, Olga
;
Wang, Bin
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/01/26
Anti -tubercular activity
DprE1 inhibitor
Benzothiazinone derivatives
Structure activity relationship
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Diterpenoids from Euphorbia lactea and their anti-HIV-1 activity
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 213, 页码: 11
作者:
Zhao, Ye
;
Hua, Chen
;
Sha, Yi-ou
;
Wu, Pei-Qian
;
Liu, Qun-Fang
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/10/17
Euphorbia lactea Haw
Euphorbiaceae
Diterpenoid
Ingol
Ent -pimarane
Anti-HIV-1
Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 80, 页码: 117177
作者:
Yu, Yuanyuan
;
Yuan, Wenlong
;
Yuan, Jiaqi
;
Wei, Wenhui
;
He, Qian
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/27
Osteoarthritis
Oleanolic acid derivatives
Anti-inflammatory
IL-1? inhibition
Antiosteoclastic activity
Recombinant cell-penetrating trichosanthin synergizes anti-PD-1 therapy in colorectal tumor
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 6, 页码: 1698-1712
作者:
Zhang, Meng
;
Liu, Ergang
;
Chen, Guihua
;
Tang, Yisi
;
Fang, Yuefei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
Trichosanthin
cell -penetrating peptide
anti -PD-1 therapy
tumor immune microenvironment
colorectal cancer
Biogenic platinum nanoparticles on bacterial fragments for enhanced radiotherapy to boost antitumor immunity
期刊论文
OAI收割
NANO TODAY, 2022, 卷号: 47, 页码: 10
作者:
Deng, Zheng
;
Liu, Jiawei
;
Xi, Min
;
Wang, Chunjie
;
Fang, Huapan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/12/29
Radiotherapy
Platinum nanoparticles
Shewanella oneidensis MR-1
Immune checkpoint blockade
Anti-tumor immunity
Construction of stable membranal CMTM6-PD-L1 full-length complex to evaluate the PD-1/PD-L1-CMTM6 interaction and develop anti-tumor anti-CMTM6 nanobody
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Jia, Xiao-min
;
Long, Yi-ru
;
Yu, Xiao-lu
;
Chen, Run-qiu
;
Gong, Li-kun
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/04/10
cancer immunotherapy
CMTM6
CMTM6
PD-L1 complex
protein interactions
anti-CMTM6 nanobody