中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
新疆理化技术研究所 [3]
中国科学院大学 [3]
海洋研究所 [3]
兰州化学物理研究所 [2]
金属研究所 [1]
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iSwitch采集 [3]
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期刊论文 [22]
学位论文 [1]
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2021 [4]
2019 [1]
2018 [3]
2017 [1]
2016 [2]
2014 [4]
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学科主题
分析化学与药物化学 [2]
Mycology [1]
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Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
  |  
收藏
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浏览/下载:56/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
人参皂苷 CK 衍生物和黄酮糖苷的合成及活性研究
学位论文
OAI收割
北京: 中国科学院大学;中国科学院生态环境研究中心, 2021
作者:
尚呈翔
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/20
人参皂苷 Ck,抗肿瘤,夏佛塔苷,降血糖,计算机辅助药物设计
ginsenoside Ck, Anti-tumor, Shaftaside, Anti-diabetic, Computer Aided Drug Design (Cadd)
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:
Jiang, Bo
;
Luo, Jiao
;
Guo, Shuju
;
Wang, Lijun
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/11
Type 2 diabetes mellitus
Protein tyrosine phosphatase 1B inhibitors
Thiazolidinedione
Insulin signaling
Anti-diabetic activities
Lignanamides from the roots of Limonium gmelinii (Willd.) Kuntze and their anti-diabetic, cytotoxic and anti-inflammatory activities.
期刊论文
OAI收割
Phytochemistry, 2021, 卷号: 184, 期号: 4, 页码: 1-10
作者:
Tuohongerbieke, Amanguli
;
Li, Jun
;
Sabir, Gulnar
;
Xin, Xuelei
;
Hu, Miao
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/03/03
Anti-diabetic
Anti-inflammatory
Cytotoxic
Lignanamides
Limonium gmelinii (Willd.) Kuntze
Plumbaginaceae
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
作者:
Li, Xiangqian
;
Xu, Qi
;
Li, Chao
;
Luo, Jiao
;
Li, Xiuxue
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/05/15
Anti-diabetic
PTP1B inhibitor
Selectivity
BKS db mice
Toxicity
Anti-diabetic Effect of Punica granatum Flower Polyphenols Extract in Type 2 Diabetic Rats: Activation of Akt/GSK-3 beta and Inhibition of IRE1 alpha-XBP1 Pathways
期刊论文
OAI收割
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Tang, Dan
;
Liu, Liu
;
Ajiakber, Dildar
;
Ye, Jianping
;
Xu, Jianjun
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
type 2 diabetes mellitus
Punica granatum L. flower
anti-diabetic herb
oral glucose tolerance test
endoplasmic reticulum stress
insulin resistance
Robust hybrid enzyme nanoreactor mediated plasmonic sensing strategy for ultrasensitive screening of anti-diabetic drug
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2018, 卷号: 99, 页码: 653-659
作者:
Wu, Di
;
Hu, Na
;
Kong, Weiheng
;
Li, Ning
;
Dai, Chunji
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2017/12/08
Hybrid enzyme hierarchical structure
alpha-glucosidase
Plasmonic sensing
Anti-diabetic drug
Anti-diabetic effect and mechanism of Kursi Wufarikun Ziyabit in L6 rat skeletal muscle cells
期刊论文
OAI收割
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2018, 卷号: 137, 期号: 2, 页码: 212-219
作者:
Edirs, S (Edirs, Salamet)[ 1,3 ]
;
Jiang, L (Jiang, Lan)[ 1,2 ]
;
Xin, XL (Xin, XueLei)[ 1,2 ]
;
Aisa, HA (Aisa, Haji Akber)[ 1,2 ]
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2018/09/27
Type 2 Diabetes
Kursi Wufarikun Ziyabit
Anti-diabetic Activity
Insulin Signaling Pathway
Endoplasmic Reticulum Stress
Anti-diabetic effect of three new norditerpenoid alkaloids in vitro and potential mechanism via PI3K/Akt signaling pathway
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 87, 期号: 3, 页码: 145-152
作者:
Tang, D (Tang, Dan)
;
Chen, QB (Chen, Qi-Bin)
;
Xin, XL (Xin, Xue-Lei)
;
Aisa, HA (Aisa, Haji-Akber)
;
Aisa, HA
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2017/04/05
Diabetes
Norditerpenoid alkaloids
Anti-diabetic activity
Glucose metabolism
Protein tyrosine phosphatase 1B
PI3K/Akt signaling pathway
Design, synthesis and evaluation of potent G-protein coupled receptor 40 agonists
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2016, 卷号: 27, 期号: 1, 页码: 159-162
作者:
Huang, Jing
;
Guo, Bin
;
Chu, Wen-Jing
;
Xie, Xin
;
Yang, Yu-She
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
GPR40
Anti-diabetic
Agonist
Phenylpropionic acid derivative