中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
生物物理研究所 [1]
金属研究所 [1]
西双版纳热带植物园 [1]
昆明植物研究所 [1]
中国科学院大学 [1]
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OAI收割 [20]
iSwitch采集 [1]
内容类型
期刊论文 [21]
发表日期
2016 [2]
2013 [2]
2012 [2]
2011 [1]
2010 [2]
2009 [1]
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学科主题
Biochemist... [3]
Chemistry [2]
Cell Biolo... [1]
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Synthesis and cytotoxicity evaluation of 4 '-amino-4 '-dehydroxyloleandrin derivatives
期刊论文
iSwitch采集
Fitoterapia, 2016, 卷号: 113, 页码: 85-90
作者:
Chen, Hu
;
Lei, Min
;
Ma, Biao
;
Liu, Miao
;
Guo, Dean
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2019/05/09
Oleandrin
Antitumor agent
Natural product
Cytotoxicity
Structure-activity relationships (sars)
Synthesis and cytotoxicity evaluation of 4 '-amino-4 '-dehydroxyloleandrin derivatives
期刊论文
OAI收割
FITOTERAPIA, 2016, 卷号: 113, 页码: 85-90
作者:
Chen, Hu
;
Lei, Min
;
Ma, Biao
;
Liu, Miao
;
Guo, Dean
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/01/08
Oleandrin
Antitumor agent
Natural product
Cytotoxicity
Structure-activity relationships (SARs)
Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway
期刊论文
OAI收割
CELL DEATH & DISEASE, 2013, 卷号: 4, 页码: e952
作者:
Lv, C.
;
Hong, Y.
;
Miao, L.
;
Li, C.
;
Xu, G.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2014/07/17
Wentilactone A
novel antitumor agent
lung cancer
Ras/Raf/ERK/p53-p21 pathway
Cytotoxic cardenolides from the root bark of Calotropis gigantea
期刊论文
OAI收割
STEROIDS, 2013, 卷号: 78, 期号: 10, 页码: 1029-1034
作者:
You, Hanyun
;
Lei, Min
;
Song, Weibin
;
Chen, Hu
;
Meng, Yuhui
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Antitumor agent
Calotropis gigantea
Asclepiadaceae
Cardenolide
Cytotoxicity
anovelsulfonamideagentmpsp001exhibitspotentactivityagainsthumancancercellsinvitrothroughdisruptionofmicrotubule
期刊论文
OAI收割
actapharmacologicasinica, 2012, 卷号: 33, 期号: 2, 页码: 261
作者:
Liu Zulong
;
Tian Wei
;
Wang Yong
;
Kuang Shan
;
Luo Xiaomin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
PHASE-I
ANTITUMOR-ACTIVITY
ANTICANCER AGENT
DRUG-RESISTANCE
SOLID TUMORS
BINDING
APOPTOSIS
TUBULIN
E7070
COLCHICINE
MPSP-001
sulfonamide
anticancer drug
microtubules
tubulin
mitotic spindle
drug resistance
drug synergism
A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 2, 页码: 261-270
作者:
Liu Zulong
;
Tian Wei
;
Wang Yong
;
Kuang Shan
;
Luo Xiaomin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/02/02
PHASE-I
ANTITUMOR-ACTIVITY
ANTICANCER AGENT
BINDING
APOPTOSIS
E7070
COLCHICINE
DISCOVERY
HMN-214
CAMPTOTHECIN
MPSP-001
sulfonamide
anticancer drug
microtubules
tubulin
mitotic spindle
drug resistance
drug synergism
Dual Carbamoylations on the Polyketide and Glycosyl Moiety by Asm21 Result in Extended Ansamitocin Biosynthesis
期刊论文
OAI收割
CHEMISTRY & BIOLOGY, 2011, 卷号: 18, 期号: 12, 页码: 1571-1580
作者:
Li, Yan
;
Zhao, Peiji
;
Kang, Qianjin
;
Ma, Juan
;
Bai, Linquan
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2012/07/25
Antitumor Agent Ansamitocin
Beta-lactam Antibiotics
Actinosynnema-pretiosum
Gene-cluster
Dna Gyrase
Concanamycin-a
Streptomyces
Novobiocin
Carbamoyltransferase
Inhibitors
Design and Synthesis of Biotinylated Troglitazone as an Active Affinity Probe
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2010, 卷号: 28, 期号: 11, 页码: 2240-2244
作者:
Li Xin
;
Li Xiaoqi
;
Tang Hong
;
Nan Fajun
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
antitumor agent
molecular mechanism
structure-activity relationship
biotinylated probe
affinity chromatography
Design and Synthesis of Biotinylated Troglitazone as an Active Affinity Probe
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2010, 卷号: 28, 期号: 11, 页码: 2240-2244
Li Xin
;
Li Xiaoqi
;
Tang Hong
;
唐宏
;
Nan Fajun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2013/12/24
antitumor agent
molecular mechanism
structure-activity relationship
biotinylated probe
affinity chromatography
Biodegradable amphiphilic polymer-drug conjugate micelles
期刊论文
OAI收割
expert opinion on drug delivery, 2009, 卷号: 6, 期号: 10, 页码: 1079-1090
Hu XL
;
Jing XB
收藏
  |  
浏览/下载:190/57
  |  
提交时间:2010/06/18
BLOCK-COPOLYMER MICELLES
RING-OPENING POLYMERIZATION
IN-VITRO
TRIBLOCK COPOLYMER
ANTITUMOR AGENT
EPSILON-CAPROLACTONES
DIBLOCK COPOLYMERS
CIRCULATION TIMES
ANTICANCER DRUGS
DELIVERY SYSTEMS