中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [31]
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上海生物化学与细胞生... [7]
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期刊论文 [66]
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Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 21
作者:
Lan, Yaohan
;
Ji, Yinchun
;
Peng, Xia
;
Duan, Wenhu
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/08/22
autoimmune disease
necroptosis inhibitor
pharmacokinetic profile
receptor interacting protein kinase 1 (RIPK1)
structural optimization
Prevalence and clinical correlates of suicide attempts in patients with first-episode drug-na?ve major depressive disorder and comorbid autoimmune thyroiditis
期刊论文
OAI收割
BJPSYCH OPEN, 2024, 卷号: 10, 期号: 3, 页码: 7
作者:
Luo, Yinli
;
Zhou, Yanan
;
Peng, Pu
;
Yuan, Ning
;
Zhang, Xiangyang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/05/27
Anxiety
autoimmune thyroiditis
major depressive disorder
suicide attempts
first-episode drug-na & iuml
ve
TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
Autoantibodies against eukaryotic translation elongation factor 1 delta in two patients with autoimmune cerebellar ataxia
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 14, 页码: 8
作者:
Guo, Liyuan
;
Ren, Haitao
;
Fan, Siyuan
;
Chao, Xingchen
;
Liu, Mange
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/04
autoimmune
cerebellar ataxia
biomarker
novel autoantibody
anti-EEF1D antibody
Autoimmune diseases: targets, biology, and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Li, Shu-jie
;
Wu, Yan-li
;
Chen, Juan-hua
;
Shen, Shi-yi
;
Duan, Jia
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/01/26
autoimmune disease
autoantigen
immunotherapy
type 1 diabetes
insulin
drug discovery
The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 123, 页码: 12
作者:
Xie, Ling
;
Lv, Jie
;
Saimaier, Kaidireya
;
Han, Sanxing
;
Han, Mengyao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
TPN10518
Th1/Th17 cells
AP1
Experimental autoimmune encephalomyelitis
Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
;
Chen, Song
;
Yu, Mingcheng
;
Zhou, Ronghui
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases
ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Guo, Cheng-cen
;
Xu, H. Eric
;
Ma, Xiong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
transcription factors
ARID
ARID3a
autoimmune diseases
systemic lupus erythematosus
primary biliary cholangitis
Clinical correlates of autoimmune thyroiditis and non-autoimmune hypothyroidism in treatment-naive patients with major depressive disorders
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2023, 卷号: 323, 页码: 755-761
作者:
Wu, Siqi
;
Wang, Haitao
;
Zhou, Yue
;
Xia, Xingzhi
;
Yue, Yan
  |  
收藏
  |  
浏览/下载:230/0
  |  
提交时间:2023/03/01
Major depressive disorder
Autoimmune thyroiditis
Subclinical hypothyroidism
Non-autoimmune hypothyroidism
Suicide attempts
Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7
作者:
Tong, Xiao
;
Chen, Li
;
He, Shi-jun
;
Zuo, Jian-ping
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/09/30
artemisinin derivative
beta-aminoarteether maleate (SM934)
autoimmune and inflammatory diseases
T helper cells
macrophages
inflammatory cytokines