中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [53]
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期刊论文 [96]
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TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
Sevoflurane Alters Serum Metabolites in Elders and Aging Mice and Increases Inflammation in Hippocampus
期刊论文
OAI收割
JOURNAL OF INFLAMMATION RESEARCH, 2024, 卷号: 17, 页码: 1241-1253
作者:
Wang, Tingting
;
Wu, Xia
;
Zhao, Xiaoli
;
Li, Jiaqi
;
Yu, Jian
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/04/09
sevoflurane
hippocampus
neuroinflammation
RNA-seq
metabolomics
isatin
The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Cui, Shi-hao
;
Suo, Na
;
Yang, Ying
;
Wu, Xuan
;
Guo, Shi-meng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/11
oligodendrocyte
oligodendrocyte progenitor cell
differentiation
remyelination
U73122
The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 123, 页码: 12
作者:
Xie, Ling
;
Lv, Jie
;
Saimaier, Kaidireya
;
Han, Sanxing
;
Han, Mengyao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
TPN10518
Th1/Th17 cells
AP1
Experimental autoimmune encephalomyelitis
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
OAI收割
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
;
Xin, Zengfeng
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
Spermine alleviates experimental autoimmune encephalomyelitis via regulating T cell activation and differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2022, 卷号: 107, 页码: 11
作者:
Zheng, Ruting
;
Kong, Miaomiao
;
Wang, Siwei
;
He, Bingqing
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/16
Spermine
Polyamines
Multiple Sclerosis
EAE
Th1
Th17
MAPK pathway
ERK
Synthesis and biological evaluation of artemisinin derivatives as potential MS agents
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 64, 页码: 5
作者:
Zhang, Yan
;
Lv, Jie
;
Zhang, Suqing
;
Yang, Hanxi
;
Shen, Jingshan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/08/16
Artemisinin derivatives
Multiple sclerosis
Th1/Th17
IFN-?/IL-17A
EAE
Tyrphostin A9 protects axons in experimental autoimmune encephalomyelitis through activation of ERKs
期刊论文
OAI收割
LIFE SCIENCES, 2022, 卷号: 294, 页码: 12
作者:
Dai, Xiaodong
;
Wang, Yongmei
;
Li, Yuexin
;
Zhong, Yongping
;
Pei, Min
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/15
Multiple sclerosis (MS)
Experimental autoimmune encephalomyelitis (EAE)
Extracellular signal-regulated kinase
Tyrphostin A9
Amelioration of Experimental Autoimmune Encephalomyelitis in Alzheimer's Disease Mouse Models: A Potential Role for A beta
期刊论文
OAI收割
CELLS, 2022, 卷号: 11, 期号: 6, 页码: 11
作者:
Shi, Changjie
;
Cha, Jiaxue
;
Gong, Junyuan
;
Wang, Shaodeng
;
Zeng, Peng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
amyloid-beta peptide
experimental autoimmune encephalomyelitis
multiple sclerosis
Alzheimer's disease
Th17
Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis
期刊论文
OAI收割
CELLULAR IMMUNOLOGY, 2022, 卷号: 373, 页码: 10
作者:
Liu, Guangyu
;
Jiang, Xiangrui
;
Han, Mengyao
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/16
EAE
Cell migration
Th1
Th17 differentiation