中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
上海神经科学研究所 [4]
上海营养与健康研究所 [2]
上海生物化学与细胞生... [1]
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OAI收割 [14]
内容类型
期刊论文 [14]
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2023 [1]
2020 [1]
2018 [3]
2016 [4]
2015 [2]
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Science & ... [3]
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浏览/检索结果:
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Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16
作者:
Yang, Ze-xian
;
Zhang, Yu
;
Wang, Qing
;
Zhang, Lei
;
Liu, Yi-fei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/12/08
Parkinson's disease
gut-brain axis
a-Synuclein
inflammation
microbiota
intestinal mouse coloclysis model
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446
作者:
Feng, Hongxuan
;
Hu, Linghao
;
Zhu, Hongwen
;
Tao, Lingxue
;
Wu, Lei
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
Blood-brain barrier
Brain ischemia
Cell cycle
Inflammation
Neuroprotection
NF-kappa B directly regulates -arrestin-1 expression and forms a negative feedback circuit in TNF-alpha-induced cell death
期刊论文
OAI收割
FASEB JOURNAL, 2018, 卷号: 32, 期号: 8, 页码: 4096-4106
作者:
Li, Juan
;
Guo, Ao
;
Wang, Qinying
;
Li, Yuanyuan
;
Lu, Jing
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/04/28
Protein-kinase-c
Beta-arrestin 2
Experimental Colitis
Gene-expression
Rat-brain
Activation
Beta-arrestin-1
Transcription
Inflammation
Deficiency
Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 29, 页码: 7611-7616
作者:
Cheng, Hao
;
Xuan, Hongwen
;
Green, Christopher D.
;
Han, Yixing
;
Sun, Na
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/09
inflammation
aging
brain
H3K27ac
gene-body acetylation
Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 29, 页码: 7611-7616
作者:
Cheng, Hao
;
Xuan, Hongwen
;
Green, Christopher D.
;
Han, Yixing
;
Sun, Na
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/09
inflammation
aging
brain
H3K27ac
gene-body acetylation
Venenum Bufonis induces rat neuroinflammation by activiating NF-kappa B pathway and attenuation of BDNF
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2016, 卷号: 186, 页码: 103-110
作者:
Bi, Qi-rui
;
Hou, Jin-jun
;
Qi, Peng
;
Ma, Chun-hua
;
Shen, Yao
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Brain-derived neurotrophic factor (BDNF)
Inflammation
Neurotoxicity NF
NF- < kappa > B pathway
Venenum Bufonis
Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 32-45
作者:
Zhou, Yu
;
Liu, Jun
;
Zheng, Mingyue
;
Zheng, Shuli
;
Jiang, Chunyi
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
5-Lipoxygenase
5-LOX inhibitors
Pyrazole derivatives
Leukotrienes-related diseases
In vivo
Benzo-fuse heterocyle
Ischemic incults
Brain inflammation
structuraloptimizationandbiologicalevaluationofl5disubstitutedpyrazole3carboxaminesaspotentinhibitorsofhuman5lipoxygenase
期刊论文
OAI收割
actapharmaceuticasinicab, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:
Zhou Yu
;
Liu Jun
;
Zheng Mingyue
;
Zheng Shuli
;
Jiang Chunyi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
5-Lipoxygenase
5-LOX inhibitors
Pyrazole derivatives
Leukotrienes-related diseases
In vivo
Benzo-fused heterocycle
Ischemic incults
Brain inflammation
Structural optimization and biological evaluation of l,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase
期刊论文
OAI收割
Acta Pharmaceutica Sinica B, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:
Zhou Yu
;
Liu Jun
;
Zheng Mingyue
;
Zheng Shuli
;
Jiang Chunyi
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/12/24
5-Lipoxygenase
5-LOX inhibitors
Pyrazole derivatives
Leukotrienes-related diseases
In vivo
Benzo-fused heterocycle
Ischemic incults
Brain inflammation
Upregulation of alphaB-crystallin expression in the substantia nigra of patients with Parkinson's disease
期刊论文
OAI收割
NEUROBIOLOGY OF AGING, 2015, 卷号: 36, 期号: 4, 页码: 1686-1691
作者:
Liu, YJ
;
Zhou, QB
;
Tang, M
;
Fu, N
;
Shao, W
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2015/12/30
PROTEASOME ACTIVATOR PA28
HEAT-SHOCK PROTEINS
B-CRYSTALLIN
PROGESTERONE-ANTAGONISM
MICROGLIAL ACTIVATION
ACUTE-INFLAMMATION
LINK PROTEIN
BRAIN
NEURONS
COMPLEX