机构

• 上海药物研究所 [16]
• 昆明植物研究所 [2]
• 广州生物医药与健康研... [1]
• 大连化学物理研究所 [1]
• 中国科学院大学 [1]
• 上海营养与健康研究所 [1]
• 更多

采集方式

• OAI收割 [22]
• iSwitch采集 [1]

内容类型

• 期刊论文 [22]
• 学位论文 [1]

发表日期

• 2025 [2]
• 2023 [2]
• 2022 [3]
• 2021 [2]
• 2020 [2]
• 2019 [1]
• 更多

学科主题

• Oncology [1]
• Research &... [1]
• 生物化学与分子生物学 [1]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A patent review of BRD4 inhibitors (2020-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 页码: 16 作者:  Chen, Yanfang;  Zhou, Huanmin;  Yu, Jiamin;  Gao, Jing;  Xue, Shengyu   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/04/01 BET  BRD4  inhibitor  cancer treatment  selectivity   BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair 期刊论文  OAI收割 TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11 作者:  Chi, Shuaishuai;  Wei, Fan;  Li, Yangsha;  Yu, Lei;  Ma, Chuyao   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/01/06 CDK4  BRD4  Breast cancer  Protein stability  DNA damage   Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078 作者:  Seydimemet, Mengnisa;  Yang, Yixuan;  Lv, Yuhan;  Liu, Jiaxiang;  Yan, Ziqin   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 DNA-encoded library technology  Pyrimidine-focusedDNA-encodedlibrary  BRD4  Affinity screening  Inhibitor   Design, synthesis, and biological evaluation of BRD4 degraders 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12 作者:  Ding, Mengyuan;  Shao, Yingying;  Sun, Danwen;  Meng, Suorina;  Zang, Yi   |  收藏  |  浏览/下载：34/0  |  提交时间：2023/04/10 PROTAC  BRD4 degradation  Leukemia  Multiple myeloma  Pulmonary fibrosis   Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13 作者:  Luo, Menglan;  Wu, Qian;  Yang, Yueyue;  Sun, Lin;  Huan, Xiajuan   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/08/30 BET inhibitor  BRD4  Bivalent inhibitor  Anticancer   Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 14 作者:  Chen, Jingjing;  He, Huixin;  Wei, Aihuan;  Li, Yalei;  Cheng, Gang   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/08/16 PROTAC  Pyrrolopyridone  BRD4 S  Selectivity   BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer 期刊论文  OAI收割 ANTIOXIDANTS, 2022, 卷号: 11 作者:  Lv, Yang;  Lv, Xiaotong;  Zhang, Jiahui;  Cao, Guozhen;  Xu, Changzhi   |  收藏  |  浏览/下载：70/0  |  提交时间：2022/05/16 small cell lung cancer  BRD4  KEAP1  Nrf2  pentose phosphate pathway   Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504 作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/05/24 Medulloblastoma  Hedgehog signaling  pathway  Drug resistance  GLI  BRD4   Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20 作者:  Chen, Jingjing;  Li, Yalei;  Zhang, Jie;  Zhang, Minmin;  Wei, Aihuan   |  收藏  |  浏览/下载：73/0  |  提交时间：2021/05/24 HDAC  BRD4  Selective dual inhibitors  Anticancer   BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis 期刊论文  OAI收割 THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12 作者:  Li, Guang;  Zheng, Yan-Hua;  Xu, Li;  Feng, Juan;  Tang, Hai-Long   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 apoptosis  BRD4 inhibitor  G1 phase cell cycle checkpoint  multiple myeloma