中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [2]
长春应用化学研究所 [2]
合肥物质科学研究院 [1]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2023 [1]
2018 [1]
2014 [1]
2008 [2]
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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 140-153
作者:
Zha, Chuantao
;
Deng, Wenjia
;
Fu, Yan
;
Tang, Shuai
;
Lan, Xiaojing
  |  
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/01/08
Structure-based drug design
Selective CDK4/6 inhibitors
Structure-activity relationship study
In vivo antitumor activity
Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73
期刊论文
OAI收割
ONCOTARGET, 2014, 卷号: 5, 期号: 17, 页码: 7691-7704
作者:
Lam, Frankie
;
Abbas, Abdullahi Y.
;
Shao, Hao
;
Teo, Theodosia
;
Adams, Julian
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
CDK9
shRNA
Mnks
eIF4E
kinase inhibitors
PI3K/Akt/mTOR
Ras/Raf/MAPK
Flavopiridol
CGP57380
apoptosis
transcription
translation
drug development
Expression, purification and spectral characterization of p21(Waf1/Cip1)
期刊论文
OAI收割
chemical research in chinese universities, 2008, 卷号: 24, 期号: 2, 页码: 192-195
Shi QY
;
Zheng YC
;
Ren JS
;
Qu XG
收藏
  |  
浏览/下载:146/9
  |  
提交时间:2010/04/14
CYCLIN-DEPENDENT KINASES
CDK INHIBITORS
PROTEIN
REGULATORS
FAMILY
Targeted RNA interference of cyclin A(2) mediated by functionalized single-walled carbon nanotubes induces proliferation arrest and apoptosis in chronic myelogenous leukemia K562 cells
期刊论文
OAI收割
chemmedchem, 2008, 卷号: 3, 期号: 6, 页码: 940-945
Wang XH
;
Ren JS
;
Qu XG
收藏
  |  
浏览/下载:141/14
  |  
提交时间:2010/04/14
A EXPRESSION
MAMMALIAN-CELLS
DNA-REPLICATION
CDK INHIBITORS
IN-VIVO
DELIVERY
TRANSPORTERS
CANCER
GENE
BIODISTRIBUTION