机构

• 上海药物研究所 [9]
• 上海营养与健康研究所 [2]
• 合肥物质科学研究院 [2]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2025 [1]
• 2021 [3]
• 2020 [1]
• 2019 [3]
• 2018 [1]
• 2017 [2]
• 更多

学科主题

• Cell Biolo... [2]

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair 期刊论文  OAI收割 TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11 作者:  Chi, Shuaishuai;  Wei, Fan;  Li, Yangsha;  Yu, Lei;  Ma, Chuyao   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/01/06 CDK4  BRD4  Breast cancer  Protein stability  DNA damage   Role of FUS-CHOP in Myxoid Liposarcoma via miR-486/CDK4 Axis 期刊论文  OAI收割 BIOCHEMICAL GENETICS, 2021 作者:  Wu, Hao;  Xia, Liming;  Xu, Haichao   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/01/10 FUS-CHOP  Myxoid liposarcoma  Apoptosis  miR-486  CDK4 axis   Molecular modeling studies of [4-(3H-benzoimidazol-5-yl)-pyrimidin-2-yl]-amine-based CDK4 inhibitors 期刊论文  OAI收割 FUTURE MEDICINAL CHEMISTRY, 2021, 卷号: 13, 期号: 16, 页码: 1317-1339 作者:  Lv, Han;  Du, Yongli;  Sheng, Xiehuang;  Gao, Zhipei;  Shen, Jingkang   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/03/21 abemaciclib  CDK4  CoMFA  CoMSIA  MD simulation  3D-QSAR   Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936 作者:  Gao, Jing;  Zhang, Hanwu;  Zhou, Fengqi;  Hou, Bo;  Chen, Meiwan   |  收藏  |  浏览/下载：59/0  |  提交时间：2021/08/17 Cancer immunotherapy  siRNA delivery  Acid-activatible micelleplex  CDK4  6 inhibitor  PD-L1 knockdown   Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma 期刊论文  OAI收割 JOURNAL OF CANCER, 2020, 卷号: 11 作者:  Zhu, Guanxia;  Li, Xia;  Li, Jiong;  Zhou, Wei;  Chen, Zhongjian   |  收藏  |  浏览/下载：38/0  |  提交时间：2020/11/30 esophageal squamous cell carcinoma  oral squamous cell carcinoma  arsenic trioxide  cyclin D1  PD-L1  CDK4/6   Simultaneous inhibition of PI3K alpha and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割 CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-+ 作者:  Wang, Yuxiang;  Li, Xian;  Liu, Xueling;  Chen, Yi;  Yang, Chunhao   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 PI3K alpha  CDK4/6  KRAS  NSCLC  CYH33   Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割 CANCER BIOLOGY & MEDICINE, 2019, 卷号: 16, 期号: 1, 页码: 66-83 作者:  Wang, Yuxiang;  Li, Xian;  Liu, Xueling;  Chen, Yi;  Yang, Chunhao   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/03/21 PI3K alpha  CDK4/6  KRAS  NSCLC  CYH33   Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer 期刊论文  OAI收割 Cancer Biology and Medicine, 2019, 卷号: 16, 期号: 1, 页码: 66 作者:  Wang Yuxiang;  Li Xian;  Liu Xueling;  Chen Yi;  Yang Chunhao   |  收藏  |  浏览/下载：35/0  |  提交时间：2020/12/24 PI3Kα  CDK4/6  KRAS  NSCLC  CYH33   Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 140-153 作者:  Zha, Chuantao;  Deng, Wenjia;  Fu, Yan;  Tang, Shuai;  Lan, Xiaojing   |  收藏  |  浏览/下载：80/0  |  提交时间：2019/01/08 Structure-based drug design  Selective CDK4/6 inhibitors  Structure-activity relationship study  In vivo antitumor activity   The steady-state level of CDK4 protein is regulated by antagonistic actions between PAQR4 and SKP2 and involved in tumorigenesis 期刊论文  OAI收割 JOURNAL OF MOLECULAR CELL BIOLOGY, 2017, 卷号: 9, 期号: 5, 页码: 409-421 作者:  Wang, Lin;  Wei, Siying;  Cao, Qianqian;  Wang, Zhenzhen;  Chen, Yan   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/12/09 CDK4  PAQR4  SKP2  ubiquitination  protein degradation  tumorigenesis