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浏览/检索结果: 共299条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2025, 页码: 14 作者:  Wen, Yiming;  Xu, Peijia;  Chen, Yijie;  Meng, Jingyi;  Zheng, Mingyue   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/04/01 p53 Y220C  Covalent stabilizer  Virtual screening  Molecular dynamics  DNA binding  Structure-activity relationship  Cancer therapy   Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16 作者:  Tang, Cai-ling;  Li, Yuan-qing;  Du, Xi-kun;  Fang, Xiao-xia;  Guang, Yi-man   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 dynamics simulation  CECR2  covalent inhibitor  allosteric effect   Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20 作者:  Luo, Menglan;  Ye, Yunfei;  Tang, Lu;  Kan, Weijuan;  Chen, Lin   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/11/26 Menin  Covalent inhibitor  Antitumor  Degradation   Synergistic immune augmentation enabled by covalently conjugating TLR4 and NOD2 agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 278, 页码: 15 作者:  Ding, Dong;  Gao, Runing;  Lei, Yujuan;  Liu, Jianing;  Zhou, Chengkai   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/10/21 TLR4 agonist  NOD2 agonist  Adjuvant  Covalent conjugation  Subunit vaccine   DNA-Encoded Noncanonical Substrate Library for Protease Profiling 期刊论文  OAI收割 CHEMBIOCHEM, 2024, 页码: 12 作者:  Zhang, Huiya;  Xing, Yuyu;  Yang, Yixuan;  Tang, Bixi;  Zong, Zhaoyun   |  收藏  |  浏览/下载：73/0  |  提交时间：2024/12/16 Protease substrate  DNA-encoded library  Combinatorial peptide library  High-throughput screening  Covalent inhibitor  Noncanonical peptide   Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer 期刊论文  OAI收割 NANO TODAY, 2024, 卷号: 58, 页码: 12 作者:  Zhang, Huijuan;  Chen, Fangmin;  Cheng, Wenhao;  Lai, Yi;  Hou, Bo   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/10/09 Polyphenol  Cuproptosis  Dynamic covalent bond  Cancer metalloimmunotherapy  Tumor immune microenvironment   Immobilization of Au nanoparticles on black phosphorus modified spherical covalent organic frameworks for the flow-through reduction of 4-nitrophenol 期刊论文  OAI收割 COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2024, 卷号: 697, 页码: 11 作者:  Wang, Ning;  Qi, Xiaole;  Xiao, Fengyan   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/10/24 Black phosphorus  Covalent organic frameworks  Au nanoparticles  Heterogeneous catalyst  4-Nitrophenol   The metal- and covalent-organic frameworks-based molecularly imprinted polymer composites for sample pretreatment 期刊论文  OAI收割 TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2024, 卷号: 178, 页码: 20 作者:  Wen, Yuhao;  Sun, Dani;  Li, Jinhua;  Ostovan, Abbas;  Wang, Xiaoyan   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/10/24 Molecularly imprinted polymers (MIPs)  Metal -organic frameworks (MOFs)  Covalent -organic frameworks (COFs)  Composite materials  Molecular recognition characteristics  Sample pretreatment  Sample preparation   Molecularly imprinted polymers and porous organic frameworks based analytical methods for disinfection by-products in water and wastewater 期刊论文  OAI收割 ENVIRONMENTAL POLLUTION, 2024, 卷号: 356, 页码: 16 作者:  Li, Jinhua   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/10/24 Disinfection by-products (DBPs)  Functional materials  Molecularly imprinted polymers (MIPs)  Metal-organic frameworks (MOFs)  Covalent-organic frameworks (COFs)  Water   Rapid isolation of extracellular vesicles using covalent organic frameworks combined with microfluidic technique 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 245, 页码: 11 作者:  Xin, Fangyuan;  Ren, Xiaohong;  Lin, Xueyuan;  Ma, Wuzhen;  Ran, Bo   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/11/26 Microfluidic  Covalent organic framework  Extracellular vesicle  Isolation