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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
广州地球化学研究所 [2]
长春光学精密机械与物... [1]
成都生物研究所 [1]
大连化学物理研究所 [1]
水生生物研究所 [1]
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采集方式
OAI收割 [11]
内容类型
期刊论文 [8]
会议论文 [2]
学位论文 [1]
发表日期
2024 [2]
2023 [1]
2018 [1]
2017 [2]
2016 [1]
2015 [1]
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学科主题
药物化学 [1]
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浏览/检索结果:
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Beyond plastic pollution: Unveiling chemical release from plastic debris in river water and seawater using non-target screening
期刊论文
OAI收割
WATER RESEARCH, 2024, 卷号: 267, 页码: 11
作者:
Peng, Xianzhi
;
Li, Xinling
;
Zhou, Jing
;
Tan, Jianhua
;
Chen, Guangshi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Plastic pollution
Chemical release
Leaching kinetics
Aquatic environment
Nontarget screening
Revealing chemical release from plastic debris in animals' digestive systems using nontarget and suspect screening and simulating digestive fluids
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2024, 卷号: 348, 页码: 10
作者:
Peng, Xianzhi
;
Yang, Tao
;
Guo, Shang
;
Zhou, Jing
;
Chen, Guangshi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/09/12
Nontarget and suspect screening
Digestive fluids
Plastic pollution
Chemical release
UHPLC-HRMS
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 650, 页码: 117-122
作者:
Ni, Yicheng
;
Luo, Zhongyuan
;
Lv, Yixin
;
Ma, Shuyuan
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
Thioredoxin reductase 1 inhibitor
Chemical probe
High -throughput screening
Thimerosal
Computational chemical biology and drug design: Facilitating protein structure, function, and modulation studies
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2018, 卷号: 38, 期号: 3, 页码: 914-950
作者:
Zheng, Mingyue
;
Zhao, Jihui
;
Cui, Chen
;
Fu, Zunyun
;
Li, Xutong
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
ADMET
chemical biology
drug design
in silico
lead optimization
molecular dynamics
polypharmacology
virtual screening
Nontargeted screening of chemical contaminants and illegal additives in food based on liquid chromatography-high resolution mass spectrometry
期刊论文
OAI收割
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2017, 卷号: 96, 页码: 89-98
作者:
Fu, Yanqing
;
Zhao, Chunxia
;
Lu, Xin
;
Xu, Guowang
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/06/20
Nontargeted Screening
Liquid Chromatography-mass Spectrometry
Food Safety
Illegal Additives
Chemical Contaminants
Establishment of a three-step method to evaluate effects of chemicals on development of zebrafish embryo/larvae
期刊论文
OAI收割
CHEMOSPHERE, 2017, 卷号: 186, 期号: 1, 页码: 209-217
作者:
Li, Guangyu
;
Ye, Huike
;
Su, Guanyong
;
Han, Zhihua
;
Xie, Congxin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/09/26
Chemical screening
CdCl2
TDCIPP
FTOH
Developmental toxicity
Morphology
Molecular screening for target of action and mode of action of toxic chemical
会议论文
OAI收割
中国浙江杭州, 2016-09-11
作者:
Jinmiao Zha
;
Wang ZJ(王子健)
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2018/12/25
mode
Molecular screening for target of action and mode of action of toxic chemical
AOP
Application of chemical biology in target identification and drug discovery
期刊论文
OAI收割
ARCHIVES OF PHARMACAL RESEARCH, 2015, 卷号: 38, 期号: 9, 页码: 1642-1650
作者:
Zhu, Yue
;
Xiao, Ting
;
Lei, Saifei
;
Zhou, Fulai
;
Wang, Ming-Wei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Chemical biology
Genomics
Proteomics
Drug discovery
Target validation
High-throughput screening (HTS)
低极性化合物的电喷雾质谱检测方法及几种中藏药材的活性成分研究
学位论文
OAI收割
博士, 2009
刘鑫
收藏
  |  
浏览/下载:145/0
  |  
提交时间:2011/05/09
传统中藏药
盐酸羟胺衍生化
化学成分
电喷雾质谱
色谱–质谱联用
羌活
长花党参
石莲叶点地梅
活性筛选
traditional Chinese and Tibetan medicine
hydroxylamine hydrochloride derivatization
chemical constituent
ESI-MS
GC/LC-MS
Notopterygium incisum
Codonopsis thalictrifolis
Androsace integra
bioassay screening
The synthesis and field emission property of carbon nanotubes on carbon fibers substrate (EI CONFERENCE)
会议论文
OAI收割
Technical Digest of the 20th International Vacuum Nanoelectronics Conference, IVNC 07, July 8, 2008 - July 12, 2008, Chicago, IL, United states
Leyong Z.
;
Weibiao W.
;
Jingqiu L.
;
Yuxue X.
;
Da L.
;
Song C.
;
Haifeng Z.
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2013/03/25
Using ferrocene as catalyst precursor
C2H2 as carbon source
carbon nanotubes (CNTs) with uniform density were synthesized on carbon fibers substrate by floating catalyst method. The morphology and microstructure were characterized by field emission scanning electron microscope (FESEM) and high-resolution transmission electron microscopy (HRTEM). The observation showed that the length of CNTs is about 2 m
the average space between adjacent CNTs is about 300 nm and the diameter of CNT is about 45 nm. The less dense "short and stubby" aligned CNTs films should have good electron field emission characteristics. The results of field emission showed that the emission current of CNTs/carbon fibers was 5 A at the field of 2.5 V/m
and the emission current can be 280 A with a field of 7 V/m (the specimen area is 0.25 cm2 and the distance between cathode and anode is 200 m). The calculation based on the F-N plot indicated that the field enhancement factor of CNTs tip is 499122. Using the conductivity and chemical stability of carbon fibers and the uniform and sparse density distribution of CNTs on carbon fibers substrate
the tip predominance of carbon nanotubes can be exerted
and simultaneously the effect of screening effects between adjacent carbon nanotubes on the field emission performance can also be effectively decreased. The CNTs synthesized on carbon fibers substrate has many predominances for the fabrication of cold cathode devices. For example
using the removability of carbon fibers
the cathode of CNTs/carbon fibers can be arbitrarily moved
enlaced or combined to form different patterns
and the cathode of CNTs/carbon fibers can be also fabricated in large size. Therefore
CNTs/carbon fibers may have potential application in field emission displays.