中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
水生生物研究所 [3]
上海神经科学研究所 [2]
西双版纳热带植物园 [1]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2024 [3]
2020 [1]
2019 [1]
2017 [1]
2016 [2]
2010 [1]
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学科主题
Neuroscien... [1]
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浏览/检索结果:
共13条,第1-10条
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Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 148, 页码: 15
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/09/26
Cyclin-dependent kinase 7
Small molecular inhibitor
Triple negative breast cancer
Thieno[3,2-d]pyrimidine derivative
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
Sexual cell cycle initiation is regulated by CDK19 and CYC9 in Tetrahymena thermophila
期刊论文
OAI收割
JOURNAL OF CELL SCIENCE, 2020, 卷号: 133, 期号: 6, 页码: 12
作者:
Maa, Yang
;
Yen, Guanxiong
;
Han, Xiaojie
;
Zhang, Jing
;
Xiong, Jie
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/02
Cell cycle
Cyclin
Cyclin-dependent kinase
Sexual reproduction
Tetrahymena thermophila
Aminocyclopropane-1-carboxylic acid is a key regulator of guard mother cell terminal division in Arabidopsis thaliana
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL BOTANY, 2019, 卷号: 70, 期号: 3, 页码: 897-907
作者:
Yin, Jiao
;
Zhang, Xiaoqian
;
Zhang, Gensong
;
Wen, Yuanyuan
;
Liang, Gang
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/04/22
Cyclin-dependent Kinase
Receptor Gene Family
Stomatal Development
Transcription Factor
Ethylene
Lineage
Protein
Differentiation
Proliferation
Responses
Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5332-5336
作者:
Fu, Yan
;
Tang, Shuai
;
Su, Yi
;
Lan, Xiaojing
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Cyclin-dependent kinase
CDK inhibitor
Structure-activity relationship
In vitro and in vivo profiling
Cdk3, a conjugation-specific cyclin-dependent kinase, is essential for the initiation of meiosis in Tetrahymena thermophila
期刊论文
OAI收割
CELL CYCLE, 2016, 卷号: 15, 期号: 18, 页码: 2506-2514
作者:
Yan, Guan-xiong
;
Zhang, Jing
;
Shodhan, Anura
;
Tian, Miao
;
Miao, Wei
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2016/11/21
conjugation
cyclin-dependent kinase
meiosis initiation
sexual reproduction
Tetrahymena thermophila
Cdk3, a conjugation-specific cyclin-dependent kinase, is essential for the initiation of meiosis in Tetrahymena thermophila
期刊论文
OAI收割
CELL CYCLE, 2016, 卷号: 15, 期号: 18, 页码: 2506-2514
作者:
Yan, Guan-xiong
;
Zhang, Jing
;
Shodhan, Anura
;
Tian, Miao
;
Miao, Wei
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/01/14
conjugation
cyclin-dependent kinase
meiosis initiation
sexual reproduction
Tetrahymena thermophila
B5, a novel pyrrole-substituted indolinone, exerts potent antitumor efficacy through G2/M cell cycle arrest
期刊论文
OAI收割
INVESTIGATIONAL NEW DRUGS, 2010, 卷号: 28, 期号: 1, 页码: 26-34
作者:
Xiong, Xishan
;
Zhang, Yingwei
;
Gao, Xiang
;
Dong, Zheyi
;
Li, Lin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Pyrrole-substituted indolinone
Cell cycle arrest
Cyclin-dependent kinase
Cdc2
Cyclin B1
PKC delta regulates cortical radial migration by stabilizing the Cdk5 activator p35
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 卷号: 106, 期号: 50, 页码: 21353-21358
Zhao, Chun-tao
;
Li, Kun
;
Li, Jun-tao
;
Zheng, Wang
;
Liang, Xu-jun
;
Geng, An-qi
;
Li, Ning
;
Yuan, Xiao-bing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2012/07/13
BDNF
neuronal migration
phosphorylation
protein stability
ubiquitin
PROTEIN-KINASE-C
CYCLIN-DEPENDENT KINASE-5
NEURONAL-SPECIFIC ACTIVATOR
DEVELOPING CEREBRAL-CORTEX
CELL-MIGRATION
UP-REGULATION
MECHANISMS
NEOCORTEX
GENE
PHOSPHORYLATION