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In vitro inhibition of six active sesquiterpenoids in zedoary turmeric oil on human liver cytochrome P450 enzymes
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 322, 页码: 10
作者:
Liu, Suyan
  |  
收藏
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浏览/下载:16/0
  |  
提交时间:2024/02/27
Sesquiterpenoids
Inhibition
CYP450s
Drug-drug interactions
Mechanism
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 7069
作者:
Zhou, Lin-Lin
;
Zhang, Tao
;
Xue, Yun
;
Yue, Chuan
;
Pan, Yihui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter
期刊论文
OAI收割
BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20
作者:
Ren, Ganglin
;
Li, Hongyan
;
Hong, Dan
;
Hu, Fangyu
;
Jin, Rongjia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
LINC00955
Colorectal cancer
Cell cycle
CDK2
PHIP
Sp1
Hybrid sterility in hermaphroditic Argopecten scallops: Mutated mitochondrial genes and abnormal expression of nuclear genes
期刊论文
OAI收割
AQUACULTURE REPORTS, 2023, 卷号: 31, 页码: 12
作者:
Yu, Tieying
;
Ning, Junhao
;
Chen, Min
;
Wang, Yuan
;
Liu, Guilong
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收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/26
Hermaphroditic Argopecten scallops
Hybrid sterility
MtDNA mutation
Energy deficiency
Gene expression
Potential roles and molecular mechanisms of bioactive ingredients in Curcumae Rhizoma against breast cancer
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 114, 页码: 18
作者:
Zhao, Peng
;
Qiu, Jianfei
;
Pan, Chaolan
;
Tang, Yunyan
;
Chen, Meijun
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收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Curcumae Rhizoma
Breast cancer
Chemoresistance
Metastasis
Curcumin
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
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收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12
作者:
Ye, Qingqing
;
Ma, Jingkun
;
Wang, Peipei
;
Wang, Chang
;
Sun, Mei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Wee1 inhibitor
Scaffold hopping
Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 108
作者:
Hu, Yiqun
;
Wen, Qingliang
;
Cai, Yefeng
;
Liu, Yunye
;
Ma, Wenli
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/23
Alantolactone
Anaplastic thyroid cancer
ROS
Pyroptosis
Apoptosis