机构

• 上海药物研究所 [10]
• 上海神经科学研究所 [5]
• 昆明动物研究所 [1]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2025 [5]
• 2022 [1]
• 2012 [1]
• 2010 [1]
• 2008 [1]
• 2007 [1]
• 更多

学科主题

• Neuroscien... [3]
• Life Scien... [1]
• Pharmacolo... [1]
• Science & ... [1]

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 AI-enhanced virtual screening approach to hit identification for GluN1/GluN3A NMDA receptor 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12 作者:  Ji, Yue-shan;  Zeng, Yue   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/12/04 N-methyl-D-aspartate receptors (NMDARs)  GluN1/GluN3A  virtual screening  shape screening  rapid overlay of chemical structures (ROCS)  bidirectional and auto-regressive transformers (BART)   Identification of small-molecule inhibitors for GluN1/GluN3A NMDA receptors via a multiscale CNN-based prediction model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9 作者:  Han, Li;  Zeng, Yue;  Qu, Zhi-yan;  Fang, Sui;  Wang, Hai-ying   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/12/04 N-methyl-D-aspartate receptors  GluN1/GluN3A  drug-target binding affinity  convolutional neural networks  ImageDTA  virtual screening   Discovery of selective GluN1/GluN3A NMDA receptor inhibitors using integrated AI and physics-based approaches 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 10 作者:  Li, Shi-wei;  Zeng, Yue;  Wu, Sa-nan;  Ma, Xin-yue;  Xu, Chao   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/09/09 N-methyl-D-aspartate receptors  GluN1/GluN3A  deep learning  molecular docking  virtual screening  binding site identification   Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13 作者:  Li, Kun;  Zeng, Yue;  Xiong, Yi-da;  Wu, Hao-chen;  Fang, Sui   |  收藏  |  浏览/下载：35/0  |  提交时间：2025/08/20 drug-target affinity prediction  virtual screening  contrastive learning  graph neural network  N-methyl-D-aspartate (NMDA) receptors  GluN3A subunit.   Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8 作者:  Wang, Shi-hang;  Zeng, Yue;  Yang, Hao;  Tian, Si-yuan;  Zhou, Yong-qi   |  收藏  |  浏览/下载：47/0  |  提交时间：2025/07/25 N-methyl-D-aspartate receptors  GluN1/GluN3A  ligand-based virtual screening  scaffold hopping  deep learning  GeminiMol   Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 13 作者:  Zeng, Yue;  Zheng, Yueming;  Zhang, Tongtong;  Ye, Fei;  Zhan, Li   |  收藏  |  浏览/下载：78/0  |  提交时间：2022/08/16 N-methyl-D-aspartate (NMDA) receptors  GluN3 subunits  WZB117  allosteric modulator  ion channels  drug discovery   Novel glycine-dependent inactivation of NMDA receptors in cultured hippocampal neurons 期刊论文  OAI收割 NEUROSCIENCE BULLETIN, 2012, 卷号: 28, 期号: 5, 页码: 550 作者:  Zhang YunFeng   |  收藏  |  浏览/下载：82/0  |  提交时间：2020/12/24 MOLECULAR DETERMINANTS  INTERNALIZATION  MODULATION  CHANNELS  SUBUNIT  glycine  N-methyl-D-aspartate receptors  calcium imaging  NMDA-NR1 subunit  hippocampal neurons  inactivation   Ion channels in neuronal survival 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2010, 卷号: 53, 期号: 3, 页码: 342-347 Wang YiZheng; Xu TianLe 收藏  |  浏览/下载：37/0  |  提交时间：2012/07/13 ion channels  neuronal survival and ischemia  GLUR6-CENTER-DOT-PSD-95-CENTER-DOT-MLK3 SIGNALING MODULE  HIPPOCAMPAL CA1 REGION  ISCHEMIC BRAIN-INJURY  D-ASPARTATE RECEPTORS  CEREBRAL-ISCHEMIA  RAT HIPPOCAMPUS  CELL-DEATH  ANTISENSE OLIGODEOXYNUCLEOTIDES  MAP KINASE  ACTIVATION   Conditioning-strength dependent involvement of NMDA NR2B subtype receptor in the basolateral nucleus of amygdala in acquisition of auditory fear memory 期刊论文  OAI收割 NEUROPHARMACOLOGY, 2008, 卷号: 55, 期号: 2, 页码: 238-246 作者:  Xiong, Zhi-Qi 收藏  |  浏览/下载：52/0  |  提交时间：2012/07/23 NR2A  NR2B  ERK  auditory fear memory  amygdala  rat  LONG-TERM-POTENTIATION  D-ASPARTATE RECEPTORS  SYNAPTIC PLASTICITY  SUBUNIT COMPOSITION  LATERAL AMYGDALA  INTRACELLULAR DOMAINS  HIPPOCAMPAL SYNAPSES  DIFFERENTIAL ROLES  MAPK CASCADE  IN-VITRO   Differential roles of NR2A- and NR2B-containing NMDA receptors in activity-dependent brain-derived neurotrophic factor gene regulation and limbic epileptogenesis 期刊论文  OAI收割 JOURNAL OF NEUROSCIENCE, 2007, 卷号: 27, 期号: 3, 页码: 542-552 作者:  Xiong, Zhi-Qi 收藏  |  浏览/下载：53/0  |  提交时间：2012/07/23 epilepsy  NR2A  NR2B  BDNF  status epilepticus  kindling  hippocampus  TEMPORAL-LOBE EPILEPSY  D-ASPARTATE RECEPTORS  FIBER SYNAPTIC REORGANIZATION  LONG-TERM POTENTIATION  SUBUNIT COMPOSITION  STATUS EPILEPTICUS  RAT-BRAIN  KINDLING DEVELOPMENT  CORTICAL-NEURONS  CEREBRAL-CORTEX