机构

• 上海药物研究所 [31]
• 长春应用化学研究所 [15]
• 金属研究所 [5]
• 大连化学物理研究所 [4]
• 福建物质结构研究所 [3]
• 化学研究所 [3]
• 更多

采集方式

• OAI收割 [73]
• iSwitch采集 [2]

内容类型

• 期刊论文 [75]

发表日期

• 2024 [3]
• 2023 [1]
• 2021 [2]
• 2019 [1]
• 2018 [2]
• 2017 [2]
• 更多

学科主题

• Biochemist... [2]
• Pharmacolo... [2]
• Biophysics [1]
• Biotechnol... [1]
• Chemistry [1]
• Materials ... [1]
• 更多

筛选

浏览/检索结果: 共75条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures 期刊论文  OAI收割 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208 作者:  Yang, Ziduo;  Zhong, Weihe;  Lv, Qiujie;  Dong, Tiejun;  Chen, Guanxing   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/01/14 Proteins  Programmable logic arrays  Three-dimensional displays  Predictive models  Graph neural networks  Data models  Convolution  Protein-ligand binding affinity  graph neural networks  inductive bias  drug-target interaction  structure-based virtual screening   Studying the Effects and Competitive Mechanisms of YOYO-1 on the Binding Characteristics of DOX and DNA Molecules Based on Surface-Enhanced Raman Spectroscopy and Molecular Docking Techniques 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 7 作者:  Li, Yanjie;  Li, Zhiwei;  Yun, Penglun;  Sun, Dan   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/07/18 SERS  molecular docking method  drug molecule  binding site  competitive mechanism   Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14 作者:  Tao, Yimin;  Lu, Wei;  Gao, Jinli;  Yang, Shuangshuang;  Ruan, Chaoyi   |  收藏  |  浏览/下载：40/0  |  提交时间：2024/03/13 antibody-drug conjugate (ADC)  bioanalysis  anti-drug antibody (ADA)  ligand binding assay (LBA)  ADA-tolerant assay   Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9 作者:  Zhou, Qingtong;  Liu, Xiao;  Neri, Dario;  Li, Wenxin;  Favalli, Nicholas   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/12/08 phosphoinositide 3-kinase  drug target  ligand  binding pocket  chemical scaffold   Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6 作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing   |  收藏  |  浏览/下载：43/0  |  提交时间：2022/01/18 Binding studies  Drug discovery  Necroptosis  RIPK1 inhibitors  Sepsis   p Metabolite Identification in the Preclinical and Clinical Phase of Drug Development 期刊论文  OAI收割 CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 838-857 作者:  Wu, Yali;  Pan, Lulu;  Chen, Zhendong;  Zheng, Yuandong;  Diao, Xingxing   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/15 Metabolite identification  drug toxicity  drug exposure  covalent-binding drug  drug safety  natural medicines   The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文  OAI收割 LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073 作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping   |  收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01 Crystal structure  tubulin  colchicine binding site  inhibitor  MT189  drug design   Roles of Albumin-Binding Proteins in Cancer Progression and Biomimetic Targeted Drug Delivery 期刊论文  OAI收割 CHEMBIOCHEM, 2018, 卷号: 19, 期号: 17, 页码: 1796-1805 作者:  Zhao, Pengfei;  Wang, Yonghui;  Wu, Aihua;  Rao, Yuefeng;  Huang, Yongzhuo   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 albumin-binding proteins  biomimetic delivery  cancer  drug delivery  nutrient transporters   Recent Trends and Applications of Molecular Modeling in GPCR-Ligand Recognition and Structure-Based Drug Design 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 7 作者:  Yuan, Xiaojing;  Xu, Yechun   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 GPCR  receptor-ligand recognition  drug design  molecular modeling  molecular dynamics  docking  binding affinity  binding pathway   Albumin Binding Domain Fusing R/K-X-X-R/K Sequence for Enhancing Tumor Delivery of Doxorubicin 期刊论文  OAI收割 MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 11, 页码: 3739-3749 作者:  Liu, Liping;  Zhang, Chun;  Li, Zenglan;  Wang, Chunyue;  Bi, Jingxiu   |  收藏  |  浏览/下载：58/0  |  提交时间：2017/12/20 Albumin Binding Domain  Rgdk  Rparpar  Doxorubicin  Peptide-drug Conjugate   首页 上一页 1 2 3 4 5 6 7 8 下一页 末页