机构

• 上海药物研究所 [9]
• 广州地球化学研究所 [3]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2024 [5]
• 2023 [2]
• 2022 [3]
• 2021 [2]
• 2019 [1]

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16 作者:  Nie, Hui-Jun;  Li, Ben-Fu;  Sun, Jingya;  Yuan, Yali;  Zhang, Zhi-Gao   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/11/26 Triple-negative breast cancer  Targeting transcription regulation  Orally bioavailable degrader  PROTAC  Cyclin-dependent Kinase 9   Discovery of KW0113 as a First and Effective PROTAC Degrader of DNMT1 Protein 期刊论文  OAI收割 CHEMMEDCHEM, 2024, 页码: 16 作者:  Wang, Huihui;  Wang, Zhaoliang;  Hu, Linghao;  Yang, Bingjie;  Zong, Liangyi   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/16 Degrader  DNMT1  DNA methylation  PROTAC   SIP-metagenomics reveals key drivers of rhizospheric Benzo[a]pyrene bioremediation via bioaugmentation with indigenous soil microbes☆ 期刊论文  OAI收割 ENVIRONMENTAL POLLUTION, 2024, 卷号: 360, 页码: 12 作者:  Zhao, Xuan;  Cheng, Xianghui;  Cai, Xixi;  Wang, Shuang;  Li, Jibing   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/09/13 Stable isotope probing (SIP)  Bioaugmentation  Rhizoremediation  benzo[a]pyrene degrader  Metagenomic  Indigenous soil microbes   Targeting EGFR with molecular degraders as a promising strategy to overcome resistance to EGFR inhibitors 期刊论文  OAI收割 FUTURE MEDICINAL CHEMISTRY, 2024, 页码: 22 作者:  Wang, Qiangfeng;  Zhu, Yumeng;  Pei, Junping   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/10/21 cancer  degrader  EGFR  lysosome-based degradation  PROTAC  resistance   Cultivation and characterization of functional-yet-uncultivable phenanthrene degraders by stable-isotope-probing and metagenomic-binning directed cultivation (SIP-MDC) 期刊论文  OAI收割 ENVIRONMENT INTERNATIONAL, 2024, 卷号: 185, 页码: 11 作者:  Li, Jibing;  Luo, Chunling;  Cai, Xixi;  Dai, Yeliang;  Zhang, Dayi   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/09/12 Stable isotope probing  Metagenome binning  Cultivation  Phenanthrene degrader  Achromobacter   In Situ Discrimination and Cultivation of Active Degraders in Soils by Genome-Directed Cultivation Assisted by SIP-Raman-Activated Cell Sorting 期刊论文  OAI收割 ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2023, 卷号: 57, 期号: 44, 页码: 17087-17098 作者:  Li, Jibing;  Zhang, Dayi;  Luo, Chunling;  Li, Bei;  Zhang, Gan   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/09/14 Raman-activated cell sorting  stable-isotope probing  genome-directed cultivation  active toluene degrader  genomic sequencing   Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2023, 页码: 10 作者:  Lin, Rongkun;  Yang, Jie;  Liu, Ting;  Wang, Mingyu;  Ke, Chongrong   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 CDK9  cyclin T1  degrader  hydrophobic tag  protein degradation   Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 18 作者:  Sun, Yaoliang;  Zhang, Ying;  Chen, Xiaoai;  Yu, Aisong;  Du, Wenhao   |  收藏  |  浏览/下载：62/0  |  提交时间：2022/08/30 NSD3  PROTAC  Degrader  Methyltransferase   Discovery of a Potent and Selective Degrader for USP7 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 卷号: 61, 期号: 33, 页码: e202204395 作者:  Pei, Yuan;  Fu, Jingfeng;  Shi, Yunkai;  Zhang, Mengmeng;  Luo, Guanghao   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/21 Apoptotic Pathway  Mutant p53  p53 Mutant Cancer Cells  PROTAC  USP7 Degrader   Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：40/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design