中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [13]
广州地球化学研究所 [3]
合肥物质科学研究院 [1]
采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2025 [4]
2024 [5]
2023 [2]
2022 [3]
2021 [2]
2019 [1]
更多
学科主题
筛选
浏览/检索结果:
共17条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
Discovery of indole derivatives as STING degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21
作者:
An, Yuxiang
;
Zhang, Yan
;
Luo, Xin
;
Lan, Yaohan
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Autoimmune diseases
Degrader
Inflammatory
PROTAC
STING
First ATG101-recruiting small molecule degrader for selective CDK9 degradation
via
autophagy-lysosome pathway
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 5, 页码: 2612-2624
作者:
Zhong, Ye
;
Xu, Jing
;
Cao, Huiying
;
Gao, Jie
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/25
Protein degradation
Hydrophobic tags
ATG101
Autophagy-lysosome pathway
CDK9
Cyclin T1
Degrader
Antitumor
Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13
作者:
Xu, Yali
;
Zhao, Wensi
;
Nie, Hui-Jun
;
Wang, Jiamin
;
Fu, Jingjing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/05/27
Chemoproteomics
Genetic code expansion
Molecular glue degrader
Photo-crosslinking
Targeted protein degradation
Recent advances in targeted degradation in the RAS pathway
期刊论文
OAI收割
FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6, 页码: 693-708
作者:
Ge, Zhiming
;
Fan, Zisheng
;
He, Wei
;
Zhou, Guizhen
;
Zhou, Yidi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/24
RAS
cancer
mutation
degrader
PROTAC
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
Discovery of KW0113 as a First and Effective PROTAC Degrader of DNMT1 Protein
期刊论文
OAI收割
CHEMMEDCHEM, 2024, 页码: 16
作者:
Wang, Huihui
;
Wang, Zhaoliang
;
Hu, Linghao
;
Yang, Bingjie
;
Zong, Liangyi
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/12/16
Degrader
DNMT1
DNA methylation
PROTAC
SIP-metagenomics reveals key drivers of rhizospheric Benzo[a]pyrene bioremediation via bioaugmentation with indigenous soil microbes☆
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2024, 卷号: 360, 页码: 12
作者:
Zhao, Xuan
;
Cheng, Xianghui
;
Cai, Xixi
;
Wang, Shuang
;
Li, Jibing
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/09/13
Stable isotope probing (SIP)
Bioaugmentation
Rhizoremediation
benzo[a]pyrene degrader
Metagenomic
Indigenous soil microbes
Targeting EGFR with molecular degraders as a promising strategy to overcome resistance to EGFR inhibitors
期刊论文
OAI收割
FUTURE MEDICINAL CHEMISTRY, 2024, 页码: 22
作者:
Wang, Qiangfeng
;
Zhu, Yumeng
;
Pei, Junping
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/10/21
cancer
degrader
EGFR
lysosome-based degradation
PROTAC
resistance
Cultivation and characterization of functional-yet-uncultivable phenanthrene degraders by stable-isotope-probing and metagenomic-binning directed cultivation (SIP-MDC)
期刊论文
OAI收割
ENVIRONMENT INTERNATIONAL, 2024, 卷号: 185, 页码: 11
作者:
Li, Jibing
;
Luo, Chunling
;
Cai, Xixi
;
Dai, Yeliang
;
Zhang, Dayi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/09/12
Stable isotope probing
Metagenome binning
Cultivation
Phenanthrene degrader
Achromobacter
In Situ Discrimination and Cultivation of Active Degraders in Soils by Genome-Directed Cultivation Assisted by SIP-Raman-Activated Cell Sorting
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2023, 卷号: 57, 期号: 44, 页码: 17087-17098
作者:
Li, Jibing
;
Zhang, Dayi
;
Luo, Chunling
;
Li, Bei
;
Zhang, Gan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/09/14
Raman-activated cell sorting
stable-isotope probing
genome-directed cultivation
active toluene degrader
genomic sequencing