中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
昆明植物研究所 [3]
过程工程研究所 [3]
昆明动物研究所 [2]
生态环境研究中心 [1]
采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2023 [1]
2019 [3]
2018 [1]
2015 [1]
2013 [1]
2012 [4]
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学科主题
Biochemist... [2]
Chemistry [1]
Chemistry,... [1]
Chemistry,... [1]
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浏览/检索结果:
共17条,第1-10条
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Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:
Munikishore,Rachakunta
;
Liu,Rui
;
Zhang,Shuqun
;
Zhao,Qin-Shi
;
Nian,Yin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/07/22
Buxus alkaloid
Structural modification
T -type calcium channel
Analgesic activity
Docking analysis
Structure -activity relationship study
BUXOZINE-C
SEMPERVIRENS
RING
CONSTITUTION
Chronic thiamethoxam exposure impairs the HPG and HPT axes in adult Chinese rare minnow (Gobiocypris rarus): Docking study, hormone levels, histology, and transcriptional responses
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 185, 页码: -
作者:
Zhu Lifei
;
Wei, Li
;
Zha, Jinmiao
;
Na, Li
;
Wang, Zijian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/09/10
Docking study
Plasma hormones
Thiamethoxam
Chinese rare minnow (Gobiocypris rants)
Synthesis and PTP1B/TCPTP Inhibitory Activity Evaluation of Novel 2,5-Disubstituted-1,3,4-thiadiazolamide Derivatives Containing Carbazole/Benzimidazole Moity
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 39, 期号: 9, 页码: 2599-2608
作者:
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
1,3,4-thiadiazolamide
carbazole
benzimidazole
synthesis
PTP1B inhibitor
molecular docking
density functional theory (DFT) study
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:
Chen, Si-Yue
;
Geng, Chang-An
;
Ma, Yun-Bao
;
Huang, Xiao-Yan
;
Yang, Xiao-Tong
  |  
收藏
  |  
浏览/下载:145/0
  |  
提交时间:2019/09/10
Gastrodia elata
Polybenzyls
Melatonin receptors
Structure-activity relationships
Docking study
A novel series of 4-methyl substituted pyrazole derivatives as potent glucagon receptor antagonists: Design, synthesis and evaluation of biological activities
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1896-1908
作者:
Shu, Shuangjie
;
Dai, Antao
;
Wang, Jiang
;
Wang, Bin
;
Feng, Yang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Pyrazole derivatives
Glucagon receptor antagonist
Docking study
Binding pocket
Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 95, 页码: 302-312
作者:
Xing, Weiqiang
;
Ai, Jing
;
Jin, Shiyu
;
Shi, Zhangxing
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Pyridazinone
c-Met inhibitor
Anticancer
Docking study
Discovery of novel 2,6-disubstituted pyridazinone derivatives as acetylcholinesterase inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 63, 页码: 95-103
作者:
Xing, Weiqiang
;
Fu, Yan
;
Shi, Zhangxing
;
Lu, Dong
;
Zhang, Haiyan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Pyridazinone
Acetylcholinesterase
Alzheimer's disease
Docking study
Structural modifications of 5,6-dihydroxypyrimidines with anti-HIV activity
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 23, 页码: 7114-7118
作者:
Guo, Di-Liang
;
Zhang, Xing-Jie
;
Wang, Rui-Rui
;
Zhou, Yu
;
Li, Zeng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Dihydroxypyrimidine
Synthesis
HIV
Integrase inhibitor
Docking study
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 5, 页码: 1976-1979
作者:
Yan, Jianwei
;
Huang, Ning
;
Li, Shukun
;
Yang, Liu-Meng
;
Xing, Weiqiang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
HIV-1 protease inhibitors
Amprenavir
Darunavir biaryl compounds
Docking study
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 5, 页码: 1976-1979
作者:
Yan JW
;
Huang N
;
Li SK
;
Yang LM
;
Xing WQ
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2012/03/19
HIV-1 protease inhibitors
Amprenavir
Darunavir biaryl compounds
Docking study