中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
大连化学物理研究所 [5]
化学研究所 [2]
武汉病毒研究所 [2]
青岛生物能源与过程研... [2]
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期刊论文 [30]
学位论文 [1]
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2024 [1]
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2019 [2]
2018 [3]
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Serial multiple mediating roles of anxiety and thyroid-stimulating hormone in the relationship between depression and psychotic symptoms in young adults with anxious depression
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 351, 页码: 8-14
作者:
Wang, Qianjin
  |  
收藏
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浏览/下载:32/0
  |  
提交时间:2024/04/15
First -episode and drug -naive
Young adults
Anxious depression
Psychotic symptoms
Mediation analysis
Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2022, 卷号: 65, 期号: 6, 页码: 1123-1145
作者:
Luo, Lu
;
Yang, Jun
;
Wang, Cheng
;
Wu, Jie
;
Li, Yafang
  |  
收藏
  |  
浏览/下载:22/0
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提交时间:2024/03/07
natural product
infectious pathogen
drug discovery
drug development
in silico analysis
Drug repurposing for cancer treatment through global propagation with a greedy algorithm in a multilayer network
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2022, 卷号: 19, 期号: 1, 页码: 74-+
作者:
Cheng, Xi
;
Zhao, Wensi
;
Zhu, Mengdi
;
Wang, Bo
;
Wang, Xuege
  |  
收藏
  |  
浏览/下载:272/0
  |  
提交时间:2024/03/21
Database
drug repurposing
machine learning
network random walk
proteomics analysis
Mechanism Study of Thermally Induced Anti-Tumor Drug Loading to Engineered Human Heavy-Chain Ferritin Nanocages Aided by Computational Analysis
期刊论文
OAI收割
BIOSENSORS-BASEL, 2021, 卷号: 11, 期号: 11, 页码: 17
作者:
Yin, Shuang
;
Liu, Yongdong
;
Dai, Sheng
;
Zhang, Bingyang
  |  
收藏
  |  
浏览/下载:42/0
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提交时间:2022/06/15
ferritin
drug delivery
thermally induced drug loading
computational analysis
Editorial: Computational Learning Models and Methods Driven by Omics for Precision Medicine
期刊论文
OAI收割
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 4
作者:
Zhu, Lei
;
Cai, Hongmin
;
Zhang, Fa
;
Zou, Quan
;
Wei, Yanjie
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收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/01
omics
machine learning
drug
RNA
disease
biomarker
network analysis
deep learning
Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds
期刊论文
OAI收割
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2020, 卷号: 10, 页码: 12
作者:
Liu, Congshan
;
Yin, Jianhai
;
Yao, Jiaqing
;
Xu, Zhijian
;
Tao, Yi
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
echinococcosis
Echinococcus multilocularis
pharmacophore modeling
virtual screenings
in vitro drug screen
cytotoxicity
E
multilocularis-infected mice
pharmacokinetics analysis
Identification of potential drug-targets by combining evolutionary information extracted from frequency profiles and molecular topological structures
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 卷号: 96, 期号: 2, 页码: 758-767
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
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收藏
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浏览/下载:25/0
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提交时间:2020/11/04
drug-target interaction
rotation forest
two-dimensional principal component analysis
Deciphering molecular mechanism behind conformational change of the Sao Paolo metallo-beta-lactamase 1 by using enhanced sampling
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2019, 页码: 12
作者:
Chen, Jianzhong
;
Wang, Jinan
;
Pang, Laixue
;
Wang, Wei
;
Zhao, Juan
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Sao paolo metallo-beta-lactamase-1
REMD simulations
normal mode analysis
principal component analysis
drug resistance of antibiotics
Single cell transcriptomic analysis of human mesenchymal stem cells reveals limited heterogeneity
期刊论文
OAI收割
CELL DEATH & DISEASE, 2019, 卷号: 10, 期号: -, 页码: UNSP 368
作者:
Huang, Yin
;
Li, Qing
;
Hu, Mingyuan
;
Wang, Yu
;
Du, Liming
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/09
Patient-derived xenograft
Tumor model
Drug response analysis
Preclinical drug testing
Personalized drug selecting
Real-time monitoring of immune responses under pathogen invasion and drug interference by integrated microfluidic device coupled with worm-based biosensor
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2018, 卷号: 110, 页码: 233-238
作者:
Hu, Liang
;
Ge, Anle
;
Wang, Xixian
;
Wang, Shanshan
;
Yue, Xinpei
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2018/12/21
Microfluidic Chip
Worm-based Biosensor
Immune Responses
In Vivo Analysis
Drug Evaluation