中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
新疆理化技术研究所 [2]
西北高原生物研究所 [1]
合肥物质科学研究院 [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2022 [1]
2021 [2]
2018 [1]
2016 [1]
2015 [1]
2013 [1]
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HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-6
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
Teaching new tricks to old dogs: A review of drug repositioning of disulfiram for cancer nanomedicine
期刊论文
OAI收割
View, 2021, 卷号: 2, 期号: 4, 页码: 20200127
作者:
Zhao, Pengfei
;
Tang, Xueping
;
Huang, Yongzhuo
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/14
combination therapy
disulfiram
drug repositioning
nanotechnology
tumor-targetingdelivery
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
OAI收割
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:
Mao, Fei
;
Wang, Huan
;
Ni, Wei
;
Zheng, Xinyu
;
Wang, Manjiong
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Alzheimer's disease
drug repositioning
dual-target inhibitor
AChE inhibition
PDE5 inhibition
Drug repurposing to target Ebola virus replication and virulence using structural systems pharmacology
期刊论文
OAI收割
BMC BIOINFORMATICS, 2016, 卷号: 17, 期号: 无, 页码: 1-12
作者:
Zhao, Zheng
;
Martin, Che
;
Fan, Raymond
;
Bourne, Philip E.
;
Xie, Lei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2017/10/30
Drug Repositioning
Infectious Disease
Indinavir
Sinefungin
Binding Site Similarity
Rna-directed Rna Polymerase
Vp24
Computational Drug Repositioning for Cancer Therapeutics
期刊论文
OAI收割
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2015, 卷号: 15, 期号: 8, 页码: 767-775
作者:
Jiao, Mingkun
;
Liu, Gang
;
Xue, Yu
;
Ding, Chunyong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Anticancer drugs
Cancer therapeutics
Computational drug repositioning
Drug discovery
Drug repositioning
Drug repurposing
Computational Study of Drugs by Integrating Omics Data with Kernel Methods
期刊论文
OAI收割
molecular informatics, 2013, 卷号: 32, 期号: 11-12, 页码: 930-941
作者:
Wang, Yongcui C.
;
Deng, Naiyang
;
Chen, Shilong
;
Wang, Yong
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2014/05/09
Omics data
Kernel methods
Data integration
Drug-targets
ATC-codes of drugs
Drug repositioning
Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking
期刊论文
OAI收割
JOURNAL OF MOLECULAR MODELING, 2012, 卷号: 18, 期号: 12, 页码: 4995-5003
作者:
Hu, Guoping
;
Li, Xi
;
Sun, Xianqiang
;
Lu, Weiqiang
;
Liu, Guixia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Drug repositioning
HIV-1 Integrase
Human LEDGF/p75 protein
Molecular docking
Protein-protein interaction