中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [49]
生态环境研究中心 [4]
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期刊论文 [76]
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GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states
期刊论文
OAI收割
BMC BIOINFORMATICS, 2024, 卷号: 25, 期号: 1, 页码: 16
作者:
Liu, Fan
;
Zhou, Han
;
Li, Xiaonong
;
Zhou, Liangliang
;
Yu, Chungong
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/06
G-protein coupled receptor
State-specific structure
Binding site
Key residue
Database
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
Identification of a carbohydrate recognition motif of purinergic receptors
期刊论文
OAI收割
ELIFE, 2023, 卷号: 12, 页码: 17
作者:
Zhao, Lifen
;
Wei, Fangyu
;
He, Xinheng
;
Dai, Antao
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/02/19
G-protein coupled receptor
sugar nucleotide
recogonition mechanism
functional motif
Human
Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929
作者:
Shen, Donghang
;
Li, Xin
;
Guo, Shimeng
;
Xie, Xin
;
Nan, Fajun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/02/27
Huntingdon's disease
G protein-coupled receptor
GPR52
alpha-methylene-gamma-butyrolactones
antagonist
The ketone body acetoacetate activates human neutrophils through FFAR2
期刊论文
OAI收割
JOURNAL OF LEUKOCYTE BIOLOGY, 2023, 卷号: 113, 期号: 6, 页码: 577-587
作者:
Martensson, Jonas
;
Bjorkman, Lena
;
Lind, Simon
;
Viklund, Moa Bjerhem
;
Zhang, Linjie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
acetoacetate
FFAR2
G-protein coupled receptor
ketone body
neutrophil
Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:
Zhao, Li-hua
;
Yuan, Qing-ning
;
Dai, An-tao
;
He, Xin-heng
;
Chen, Chuan-wei
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/04/10
G protein- coupled receptors
parathyroid hormone
PTH-related peptide
PTH receptor-1
cryo-electron microscopy structure
osteoporosis
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:
Jiao, Ting-ying
;
Ma, Yuan-di
;
Guo, Xiao-zhen
;
Ye, Yun-fei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
bile acids
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
drug target
Farnesoid X receptor
G protein-coupled bile acid receptor
Computational characterization of transducer recognition of 132 adrenergic receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 卷号: 592, 页码: 67-73
作者:
Zhao, Lifen
;
He, Xinheng
;
Jiang, Hualiang
;
Cheng, Xi
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/06/15
Class A G-protein coupled receptor
Coupling selectivity
Transducer-binding interface
Functional signal
Complex models
Modulating effects of RAMPs on signaling profiles of the glucagon receptor family
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 2, 页码: 637-650
作者:
Shao, Lijun
;
Chen, Yan
;
Zhang, Shikai
;
Zhang, Zhihui
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/15
G protein-coupled receptor
Glucagon receptor family
Receptor activity-modulating protein
Signaling
Allosteric modulation
GPCR-RAMP interaction
Receptor pharmacology
Ligand selectivity
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin