中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
过程工程研究所 [10]
金属研究所 [2]
武汉植物园 [2]
力学研究所 [1]
上海药物研究所 [1]
武汉病毒研究所 [1]
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OAI收割 [18]
iSwitch采集 [3]
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期刊论文 [21]
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2023 [1]
2020 [1]
2018 [3]
2017 [1]
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Biochemist... [1]
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A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8
作者:
Chen, Wuhong
;
Gong, Ying
;
Long, Guozhang
;
Wang, Xinran
;
Yang, Yurong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
HBV
Capsid assembly modulators
Prodrug
Hepatitis B surface antigen
基于疫苗颗粒完整性的硅胶吸附/解吸附纯化重组乙肝表面抗原工艺研究
期刊论文
OAI收割
过程工程学报, 2020, 卷号: 20, 期号: 10, 页码: 1198
作者:
胡胜杰
;
黄永东
;
赵岚
;
朱凯
;
苗壮
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/03/29
hepatitis B surface antigen
particle integrity
silica gel adsorption/desorption
response surface methodology
hydrophobic interaction chromatography
乙肝表面抗原
颗粒完整性
硅胶吸附/解吸附
响应面法
疏水层析
Hepatitis B surface antigen with N-terminal addition of mCherry can assemble into functional subviral particles
期刊论文
OAI收割
FUTURE VIROLOGY, 2018, 卷号: 13, 期号: 11, 页码: 769-778
作者:
Zhou, Yuan
;
Wu, Chunchen
;
Chen, Xinwen
;
Hu, Xue
;
Chen, Jizheng
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2019/03/05
fluorescent protein
hepatitis B surface antigen
imaging
mCherry
signal peptide
subviral particles
Hepatitis B surface antigen with N-terminal addition of mCherry can assemble into functional subviral particles
期刊论文
OAI收割
FUTURE VIROLOGY, 2018, 卷号: 13, 期号: 11, 页码: 769-778
作者:
Zhou, Yuan
;
Wu, Chunchen
;
Chen, Xinwen
;
Hu, Xue
;
Chen, Jizheng
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/03/05
fluorescent protein
hepatitis B surface antigen
imaging
mCherry
signal peptide
subviral particles
Hepatitis b virus infection: defective surface antigen expression and pathogenesis
期刊论文
iSwitch采集
World journal of gastroenterology, 2018, 卷号: 24, 期号: 31, 页码: 3488-3499
作者:
Wu, Chun-Chen
;
Chen, Ying-Shan
;
Cao, Liang
;
Chen, Xin-Wen
;
Lu, Meng-Ji
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/05/08
Hepatitis b surface protein
Defective surface antigen mutants
Endoplasmic reticulum stress
Fulminant hepatitis b
Occult hepatitis b virus infection
Pathogenesis
Enhanced fluorescence elisa based on hat triggering fluorescence "turn-on" with enzyme-antibody dual labeled aunp probes for ultrasensitive detection of afp and hbsag
期刊论文
iSwitch采集
Acs applied materials & interfaces, 2017, 卷号: 9, 期号: 11, 页码: 9369-9377
作者:
Wu, Yudong
;
Guo, Weisheng
;
Peng, Weipan
;
Zhao, Qan
;
Piao, Jiafang
收藏
  |  
浏览/下载:179/0
  |  
提交时间:2019/04/23
Fluorescence enzyme-linked immunosorbent assay
Gold nanoparticles
Human alpha-thrombin
Alpha fetoprotein
Hepatitis b virus surface antigen
Asymmetrical flow field-flow fractionation coupled with multi-angle laser light scattering for stability comparison of virus-like particles in different solution environments
期刊论文
OAI收割
VACCINE, 2016, 卷号: 34, 期号: 27, 页码: 3164-3170
作者:
Chen, Yi
;
Zhang, Yan
;
Zhou, Yuefang
;
Luo, Jian
;
Su, Zhiguo
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2016/08/22
Asymmetrical flow field-flow fractionation
Virus-like particle
Antigenicity
Hepatitis B surface antigen
Aggregation
Aggregation and antigenicity of virus like particle in salt solution-A case study with hepatitis B surface antigen
期刊论文
OAI收割
VACCINE, 2015, 卷号: 33, 期号: 35, 页码: 4300-4306
作者:
Chen, Yi
;
Zhang, Yan
;
Quan, Can
;
Luo, Jian
;
Yang, Yanli
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2015/10/26
Asymmetrical flow field-flow fractionation
Virus-like particle
Aggregation
Antigenicity
Hepatitis B surface antigen
Microcalorimetric study of adsorption and disassembling of virus-like particles on anion exchange chromatography media
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2015, 卷号: 1388, 期号: APR, 页码: 195-206
作者:
Yu, Mengran
;
Zhang, Songping
;
Zhang, Yan
;
Yang, Yanli
;
Ma, Guanghui
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2015/05/12
Isothermal titration calorimetry
Hepatitis B virus surface antigen
Virus-like particles
Gigaporous media
Ion exchange chromatography
Conformational change
Design, Synthesis and Biological Evaluation of Caudatin Analogs as Potent Hepatitis B Virus Inhibitors
期刊论文
OAI收割
MEDICINAL CHEMISTRY, 2015, 卷号: 11, 期号: 2, 页码: 165-179
作者:
Wang, Li-Jun
;
Chen, Hao
;
Ma, Yun-Bao
;
Huang, Xiao-Yan
;
Geng, Chang-An
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2015/06/29
Anti-HBV activity
Caudatin analogs
Hepatitis B e Antigen (HBeAg)
Hepatitis B Surface Antigen (HBsAg)
HBV DNA replication
Structure-activity relationships(SARs)
Synthesis