中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [21]
上海生物化学与细胞生... [6]
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期刊论文 [52]
学位论文 [1]
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Hepatic Sam68 Regulates Systemic Glucose Homeostasis and Insulin Sensitivity
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 19, 页码: 14
作者:
Qiao, Aijun
;
Ma, Wenxia
;
Jiang, Ying
;
Han, Chaoshan
;
Yan, Baolong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Sam68
hepatocytes
gluconeogenesis
high-fat diet
diabetes
CRTC2
insulin sensitivity
glucagon
glucose metabolism
protein-protein interaction
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
期刊论文
OAI收割
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:
Li N(李宁)
;
Zhang XY(张晓宇)
;
Zhou J(周瑾)
;
Li W(李旺)
;
Shu XY(舒芯钰)
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/10/23
Liver tissue stiffness
Shear stress
Hydrostatic pressure
Hepatocytes
Hepatocellular carcinoma
Liver sinusoidal endothelial cells
Hepatic stellate cells
Mechanotransduction pathways
Mechanomedicine
Drug design and delivery
FEK self-assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening
期刊论文
OAI收割
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2022, 页码: 13
作者:
He, Ting
;
Qiao, Shida
;
Ma, Chen
;
Peng, Zhaoliang
;
Wu, Zhitao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
biliary excretion index
FEFEFKFK self-assembling peptide hydrogel
metabolic enzymes
rat primary hepatocytes
sandwich culture
transporters
Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy
期刊论文
OAI收割
STEM CELL RESEARCH & THERAPY, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Ma, Chen
;
Zhang, Ludi
;
He, Ting
;
Cao, Huiying
;
Ren, Xiongzhao
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
Raman spectroscopy
Cell therapy
Identification
Proliferating human hepatocytes
Dedifferentiation
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Ge, Xin-yu
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Ren, Yu-ran
;
Ye, Yang-liang
;
Feng, Ying
;
Xu, Ti-fei
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
SL010110
gluconeogenesis
primary mouse hepatocytes
PEPCK1
acetylation
degradation
Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model
期刊论文
OAI收割
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 3, 2020, 卷号: 320, 页码: G272-G282
作者:
Li W(李旺)
;
Li PW(李培文)
;
Li N(李宁)
;
Du Y(杜宇)
;
Lv SQ(吕守芹)
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2022/10/25
hepatocytes
liver fibrosis
matrix stiffness
shear flow
three-dimensional liver sinusoidal model
Nimesulide increases the aldehyde oxidase activity of humans and rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Zhou, Lei
;
Pang, Xiao-yan
;
Hou, Xiang-yu
;
Liu, Lu
;
Guo, Zi-tao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
nimesulide
aldehyde oxidase
induction
methotrexate
hepatocytes
pharmacokinetics
drug interaction
Understanding the Multiple Effects of PCBs on Lipid Metabolism
期刊论文
OAI收割
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2020, 卷号: 13, 页码: 3691-3702
作者:
Shan, Qiuli
;
Li, Hongmei
;
Chen, Ningning
;
Qu, Fan
;
Guo, Jing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2021/09/14
PCBs
metabolism-disrupting chemicals
hepatocytes
lipid metabolism
基于胚胎干细胞模型研究环境污染物对神经肝脏发育的干扰效应
学位论文
OAI收割
北京: 中国科学院生态环境研究中心, 2019
作者:
梁胜贤
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/17
环境污染物, 胚胎干细胞, 神经发育 毒性,肝 脏发育 毒性
Environmental Pollutants, Embryonic Stem Cells, Developmental Neural Toxicity, Developmental Hepatocytes Toxicity