中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [20]
上海营养与健康研究... [17]
上海生物化学与细胞生... [6]
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期刊论文 [48]
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Human-Induced Hepatocytes-Derived Extracellular Vesicles Ameliorated Liver Fibrosis in Mice Via Suppression of TGF-beta 1/Smad Signaling and Activation of Nrf2/HO-1 Signaling
期刊论文
OAI收割
STEM CELLS AND DEVELOPMENT, 2023, 页码: 14
作者:
Liu, Wenjing
;
Wu, Jiajun
;
Cao, Huiying
;
Ma, Chen
;
Wu, Zhitao
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
hepatic stellate cell activation
liver fibrosis
extracellular vesicles
human-induced hepatocyte
TGF-beta 1/Smad pathway
Nrf2/HO-1 pathway
Small molecule drugs promote repopulation of transplanted hepatocytes by stimulating cell dedifferentiation
期刊论文
OAI收割
JHEP REPORTS, 2023, 卷号: 5, 期号: 4, 页码: 11
作者:
Jiang, Mengmeng
;
Guo, Ren
;
Ai, Yan
;
Wang, Gang
;
Tang, Peilan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/10/17
Hepatocyte transplantation
Hepatocyte expansion
Dedifferentiation
Hepatocyte progenitor cells
Small molecule compounds
IL6 supports long-term expansion of hepatocytes in vitro
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 13
作者:
Guo, Ren
;
Jiang, Mengmeng
;
Wang, Gang
;
Li, Bing
;
Jia, Xiaohui
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/04/10
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466
作者:
Sun, Renqiang
;
Zhang, Zhiyong
;
Bao, Ruoxuan
;
Guo, Xiaozhen
;
Gu, Yuan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
SIRT5
bile acid
macrophage polarization
immunosuppressive tumor microenvironment
liver cancer
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 20
作者:
Zhao, Zhuohui
;
Deng, Zhen-Tao
;
Huang, Suling
;
Ning, Mengmeng
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/16
Alisol B
non-alcoholic steatohepatitis
RAR alpha
CD36
Transforming primary human hepatocytes into hepatocellular carcinoma with genetically defined factors
期刊论文
OAI收割
EMBO REPORTS, 2022, 页码: 17
作者:
Jiang, Zhiwu
;
Cheng, Lin
;
Wu, Zhiping
;
Zhou, Linfu
;
Wang, Haitao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
biomarkers
hepatocellular carcinoma
humanized mouse models
immunotherapy
oncogenes
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Ren, Yu-ran
;
Ye, Yang-liang
;
Feng, Ying
;
Xu, Ti-fei
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
SL010110
gluconeogenesis
primary mouse hepatocytes
PEPCK1
acetylation
degradation
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
OAI收割
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP
TCDD promotes liver fibrosis through disordering systemic and hepatic iron homeostasis
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2020, 卷号: 395, 页码: 1-8
作者:
Li, Changying
;
Liu, Yingying
;
Dong, Zheng
;
Xu, Ming
;
Gao, Ming
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/09/14
TCDD
Liver fibrosis
Cideb
Hepatocyte apoptosis
Iron deposition
Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407
作者:
Li, Zhiqiang
;
Li, Xinzhi
;
Su, Ming-Bo
;
Gao, Li-Xin
;
Zhou, Yu-Bo
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01