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浏览/检索结果: 共13条，第1-10条 帮助

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Open-pFind Verified Four Missing Proteins from Multi-Tissues 期刊论文  OAI收割
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 12, 页码: 4808-4814
作者:  Wu, Shujia;  Sun, Jinshuai;  Wang, Xi;  Xu, Feng;  Chi, Hao
  |  收藏  |  浏览/下载：46/0  |  提交时间：2021/12/01
食用蔬菜能吸收和积累微塑料 期刊论文  OAI收割
科学通报, 2019, 卷号: 64, 期号: 9, 页码: 928-934
作者:  李连祯;  周倩;  尹娜;  涂晨;  骆永明
  |  收藏  |  浏览/下载：142/0  |  提交时间：2020/06/17
微塑料  生菜  聚苯乙烯微球  吸收  积累  健康风险  microplastics  lettuce  polystyrene microbeads  uptake  accumulation  human health risk  Microplastic (MP, 100 nm-5 mm) may present an attributable risk to ecosystem and human health, and its pollution has become a global environmental concern. Despite a wealth of information on the accumulation of MPs in aquatic species, there is no information on the uptake and accumulation of MPs by higher plants. Terrestrial edible plants are directly exposed to MPs when agricultural soil was applied with organic manure, sewage sludge as fertilizer or plastic mulching. In this paper, the uptake of two sizes of polystyrene (PS) microbeads (0.2 and 1.0 mum) and then their distribution and migration in an edible plant lettuce were firstly investigated based on laboratory experiments. We used fluorescent markers to track PS microbeads in plant tissues and found fluorescence to be a sensitive and reliable detection method. Sections from untreated control lettuce showed no autofluorescence. When roots were treated with fluorescently labeled PS microbeads, the microbeads could be identified by its fluorescence. Our main study investigated the uptake of 0.2 mum beads, as few luminescence signals were observed in lettuce roots for 1.0 mum beads in our experiment. We observed that 0.2 mum fluorescent microbeads were extracellularly trapped in the root cap mucilage (which is a highly hydrated polysaccharide) and a dark green tip (which was typical of lettuce roots exposed to label PS beads) was usually visible to the naked eye. Confocal images revealed that the PS luminescence signals were mainly located in the vascular system and on the cell walls of the cortex tissue of the roots, indicated that the beads passed through the intercellular space via the apoplastic transport system. Once inside the central cylinder, the 0.2 mum PS beads were transferred from the roots to the stems and leaves via the vascular system following the transpiration stream. We also observed that the PS beads adhered to one another and self-assembled systematically into grape-like and (chain) string-like clusters in the intercellular space of the root and stem vascular tissue of lettuce plant. In contrast to the root and stem, PS beads were dispersed in the leaf tissue. Here, for the first time we provide evidence of the adherence, uptake, accumulation, and translocation of submicrometer MPs within an edible plant. Our findings highlight the previously underappreciated human exposure pathway to MPs through the consumption of contaminated crops and emphasize the need for new management strategies to control the release of MPs waste products into the terrestrial environment. Ultimately, the potential impacts of low range sized MPs on food safety of crop plants and human health need to be urgently considered.  
Evaluation Selenocysteine Protective Effect in Carbon Disulfide Induced Hepatitis with a Mitochondrial Targeting Ratiometric Near-Infrared Fluorescent Probe 期刊论文  OAI收割
ANALYTICAL CHEMISTRY, 2018, 卷号: 90, 期号: 13, 页码: 8108-8115
作者:  Han, Xiaoyue;  Wang, Rui;  Song, Xinyu;  Yu, Fabiao;  Chen, Lingxin
  |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/08
Steroid bioaccumulation profiles in typical freshwater aquaculture environments of South China and their human health risks via fish consumption 期刊论文  OAI收割
ENVIRONMENTAL POLLUTION, 2017, 卷号: 228, 页码: 72-81
作者:  Liu, S;  Xu, XR;  Qi, ZH;  Chen, H;  Hao, QW
收藏  |  浏览/下载：37/0  |  提交时间：2017/09/08
Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes 期刊论文  OAI收割
drug metabolism and pharmacokinetics, 2015, 卷号: 30, 期号: 5, 页码: 358-365
作者:  Lv, Xia;  Hou, Jie;  Xia, Yang-Liu;  Ning, Jing;  He, Gui-Yuan
收藏  |  浏览/下载：28/0  |  提交时间：2015/11/17
De novo identification and quantification of single amino-acid variants in human brain 期刊论文  OAI收割
JOURNAL OF MOLECULAR CELL BIOLOGY, 2014, 卷号: 6, 期号: 5, 页码: 421-433
作者:  Su, ZD;  Sheng, QH;  Li, QR;  Chi, H;  Jiang, X
收藏  |  浏览/下载：34/0  |  提交时间：2015/07/22
De novo identification and quantification of single amino-acid variants in human brain RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction High-accuracy mapping of protein binding stability on nucleosomal DNA using a single-molecule method 期刊论文  OAI收割
Journal of Molecular Cell Biology, 2014, 卷号: 6, 期号: 5, 页码: 421
作者:  Su Zhiduan;  Sheng Quanhu;  Li Qingrun;  Chi Hao;  Jiang Xi
  |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/04
Cartilage oligomeric matrix protein (COMP)-mediated cell differentiation to proteolysis mechanism networks from human normal adjacent tissues to lung adenocarcinoma 期刊论文  OAI收割
ANALYTICAL CELLULAR PATHOLOGY, 2013, 卷号: 36, 期号: 3-4, 页码: 93-105
作者:  Wang, Lin;  Huang, Juxiang;  Jiang, Minghu;  Diao, Haizhen;  Zhou, Huilei
  |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
Human brain cancer studied by resonance Raman spectroscopy 期刊论文  OAI收割
JOURNAL OF BIOMEDICAL OPTICS, 2012, 卷号: 17, 期号: 11
Zhou, Y; Liu, CH; Sun, Y; Pu, Y; Boydston-White, S; Liu, YL; Alfano, RR
收藏  |  浏览/下载：40/0  |  提交时间：2013/09/17
氯系阻燃剂得克隆的母胎/母婴暴露研究 学位论文  OAI收割
硕士, 北京: 中国科学院研究生院, 2012
作者:  贲玉婕
收藏  |  浏览/下载：36/0  |  提交时间：2017/01/06