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浏览/检索结果: 共1402条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13 作者:  Wu, Feifei;  Li, Huiyu;  Li, Weiqiang;  Zhang, Laishun;  An, Qi   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/04/01 Optimization  Hematopoietic progenitor kinase 1  Inhibitor  Cancer immunotherapy   A patent review of BRD4 inhibitors (2020-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 页码: 16 作者:  Chen, Yanfang;  Zhou, Huanmin;  Yu, Jiamin;  Gao, Jing;  Xue, Shengyu   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/04/01 BET  BRD4  inhibitor  cancer treatment  selectivity   IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Novel conjugated 5-alkenyl rhodanine tethered 1,4-benzodioxane derivatives as dual-chitinases inhibitors to hinder the growth of Asian corn borer 期刊论文  OAI收割 MEDICINAL CHEMISTRY RESEARCH, 2025, 页码: 13 作者:     |  收藏  |  浏览/下载：4/0  |  提交时间：2025/04/01 O. furnacalis  Chitinase  5-alkenylthiazolidinone  1,4-benzodioxane  Dual-chitinases inhibitor   Novel 5-alkenylthiothiazolidinone scaffold discovery as Multi-Chitinases inhibitors to arrest the molting of Asian corn borer 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1321, 页码: 11 作者:  Shi, Dongmei;  Ji, Xinge;  Zou, Renxuan;  Jiang, Zhiyang;  Duan, Yangwei   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/10/21 5-alkenylthiothiazolidinone scaffold  Multichitinase inhibitor  Amide bond  Asian corn borer  insect growth regulator   Nano-Polymers as Cas9 Inhibitors 期刊论文  OAI收割 POLYMERS, 2025, 卷号: 17, 期号: 3, 页码: 16 作者:  Chepurna, Oksana;  Chatterjee, Avradip;  Li, Yuanqing;  Ding, Hong;  Murali, Ramachandran   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/04/01 CRISPR/Cas9  nano-polymer  inhibitor  polymalic acid  polyglutamic acid  polyaspartic acid  trileucine   Hemodynamic and Pharmacokinetic Interactions of TPN171 with Alcohol in Healthy Male Subjects 期刊论文  OAI收割 CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2025, 卷号: 18, 期号: 2, 页码: 8 作者:  Cheng, Jie;  Qian, Hongjie;  Wang, Yu;  Liang, Liyu;  Xu, Wenjing   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/04/01 alcohol  healthy subjects  hemodynamics  PDE5 inhibitor  pharmacokinetics  TPN171   Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16 作者:  Tang, Cai-ling;  Li, Yuan-qing;  Du, Xi-kun;  Fang, Xiao-xia;  Guang, Yi-man   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 dynamics simulation  CECR2  covalent inhibitor  allosteric effect   Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c] pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 438-466 作者:  Li, Yang;  Fang, Yan;  Chen, Xiaoyu;  Tong, Linjiang;  Feng, Fang   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 P21-activated kinase 4  Tetrahydrobenzofuro[2  3-c]pyridine  Structure-activity relationship  Allosteric inhibitor  Pharmacokinetics properties  Kinase selectivity  Pancreatic cancer  Immune infiltration   Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12, 页码: 20 作者:  Wang, Hua;  Tang, Shijie;  Wu, Qibiao;  He, Yayi   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/02/28 EGFR-mutant lung cancer  adeno-to-squamous transition  tyrosine kinase inhibitor resistance  transcription factor network  RAPGEF3