中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
金属研究所 [5]
长春应用化学研究所 [4]
上海应用物理研究所 [2]
宁波材料技术与工程研... [1]
生态环境研究中心 [1]
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OAI收割 [21]
内容类型
期刊论文 [21]
发表日期
2026 [1]
2020 [1]
2019 [1]
2018 [3]
2014 [3]
2013 [4]
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学科主题
Chemistry [2]
Oncology [1]
Pharmacolo... [1]
Plant Scie... [1]
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Design, synthesis and biological evaluation of novel pyrrolo[1,2-b]pyridazin-2(1
H
)-ones as selective PARP1 inhibitors for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 16
作者:
He, Qiaolin
;
He, Jing
;
Huan, Xiajuan
;
Song, Shanshan
;
Zhang, Xiaofei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2026/04/01
PARP1 inhibitor
Subtype selectivity
Synthetic lethality
In vitro cytotoxicity
Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds
期刊论文
OAI收割
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2020, 卷号: 10, 页码: 12
作者:
Liu, Congshan
;
Yin, Jianhai
;
Yao, Jiaqing
;
Xu, Zhijian
;
Tao, Yi
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/07/01
echinococcosis
Echinococcus multilocularis
pharmacophore modeling
virtual screenings
in vitro drug screen
cytotoxicity
E
multilocularis-infected mice
pharmacokinetics analysis
Live-cell imaging of octaarginine-modified polymer dots via single particle tracking
期刊论文
OAI收割
CELL PROLIFERATION, 2019, 卷号: 52, 期号: 2, 页码: —
作者:
Luo, Y
;
Han, YP
;
Hu, XJ
;
Yin, M
;
Wu, CF
  |  
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2019/12/30
QUANTUM DOTS
INTRACELLULAR-TRANSPORT
PENETRATING PEPTIDES
DNA NANOSTRUCTURES
SIRNA DELIVERY
IN-VITRO
NANOPARTICLES
ENDOCYTOSIS
AUTOPHAGY
CYTOTOXICITY
Deciphering active biocompatibility of iron oxide nanoparticles from their intrinsic antagonism
期刊论文
OAI收割
NANO RESEARCH, 2018, 卷号: 11, 期号: 5, 页码: 2746-2755
作者:
Wang, L
;
Wang, ZJ
;
Li, XM
;
Zhang, Y
;
Yin, M
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2018/09/06
Mesenchymal Stem-cells
Magnetic Nanoparticles
Induced Autophagy
Oxidative Stress
Cancer-cells
In-vitro
Cytotoxicity
Apoptosis
Graphene
Therapy
Preliminary investigation on cytotoxicity of fluorinated polymer nanoparticles
期刊论文
OAI收割
Journal of Environmental Sciences, 2018, 卷号: 69
作者:
Wang Xue
;
Cheng Wenge
;
Yang Qiuyuan
;
Niu Hongyun
;
Liu Qian
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2020/11/23
F-19 MAGNETIC-RESONANCE
GRAPHENE OXIDE
PERFLUOROOCTANE SULFONATE
IN-VITRO
CELLS
TOXICITY
DAMAGE
LIVER
METABOLISM
MECHANISMS
Fluorinated nanoparticles
Polymer
Cytotoxicity
Oxidative stress
Health risk
targetingthepi3kaktmtorsignalingpathwaybypterostilbeneattenuatesmantlecelllymphomaprogression
期刊论文
OAI收割
actabiochimicaetbiophysicasinica, 2018, 卷号: 50, 期号: 8, 页码: 782
作者:
Yu Dandan
;
Zhang Yong
;
Chen Gege
;
Xie Yongsheng
;
Xu Zhijian
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
PROTEIN-KINASE PATHWAY
CANCER IN-VITRO
TRANSDUCTION PATHWAYS
CYCLE ARREST
APOPTOSIS
ACTIVATION
PATHOGENESIS
INHIBITION
ANTICANCER
EXPRESSION
mantle cell lymphoma
pterostilbene
antiproliferative activity
PI3K/Akt/mTOR pathway
synergistic cytotoxicity
Cytotoxic Effect on Osteosarcoma MG-63 Cells by Degradation of Magnesium
期刊论文
OAI收割
Journal of Materials Science & Technology, 2014, 卷号: 30, 期号: 9, 页码: 888-893
M. Li
;
L. Ren
;
L. H. Li
;
P. He
;
G. B. Lan
;
Y. Zhang
;
K. Yang
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2015/01/14
Magnesium
Biodegradation
Osteosarcoma
Cytotoxicity
in-vitro
bone
mechanisms
scaffolds
adhesion
implants
alloy
Fluoride Conversion Coating on Biodegradable AZ31B Magnesium Alloy
期刊论文
OAI收割
Journal of Materials Science & Technology, 2014, 卷号: 30, 期号: 7, 页码: 666-674
T. T. Yan
;
L. L. Tan
;
B. C. Zhang
;
K. Yang
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2015/01/14
AZ31B magnesium
Fluoride coating
Corrosion resistance
Cytotoxicity
Antibacterial
in-vitro
biomedical application
mechanical-properties
corrosion
properties
sodium-fluoride
stainless-steel
bone
implants
surface
mg
Application of the SOS/umu test and high-content in vitro micronucleus test to determine genotoxicity and cytotoxicity of nine benzothiazoles
期刊论文
OAI收割
JOURNAL OF APPLIED TOXICOLOGY, 2014, 卷号: 34, 期号: 12, 页码: 1400-1408
Yan Ye
;
Jiang Weiwei
;
Li Na
;
Ma Mei
;
Rao Kaifeng
;
Wang Zijian
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2015/03/26
benzothiazoles
SOS
umu test
High-Content in vitro Micronucleus test
genotoxicity
cytotoxicity
A Comparison of Corrosion Behavior in Saline Environment: Rare Earth Metals (Y, Nd, Gd, Dy) for Alloying of Biodegradable Magnesium Alloys
期刊论文
OAI收割
Journal of Materials Science & Technology, 2013, 卷号: 29, 期号: 9, 页码: 781-787
X. Zhao
;
L. L. Shi
;
J. Xu
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2013/12/24
Rare earth
Biodegradable metal
Magnesium alloy
Corrosion behavior
simulated body-fluids
mechanical-properties
in-vitro
part ii
cytotoxicity
microstructure
degradation
passivity
elements
stents