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Design, synthesis and biological evaluation of novel pyrrolo[1,2-b]pyridazin-2(1
H
)-ones as selective PARP1 inhibitors for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 16
作者:
He, Qiaolin
;
He, Jing
;
Huan, Xiajuan
;
Song, Shanshan
;
Zhang, Xiaofei
  |  
收藏
  |  
Discovery and optimization of Menin-MLL inhibitors targeting acute myeloid leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 15
作者:
Xiao, Qitao
;
Wang, Yuxian
;
Shen, Zheyuan
;
Mo, Jun
;
Li, Cong
  |  
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  |  
Discovery and molecular mechanism of a novel antihypertensive peptide from
Chlamydomonas
reinhardtii
based on molecular docking, molecular dynamics simulation,
in
vitro,
and
in
vivo
analysis
期刊论文
OAI收割
FOOD RESEARCH INTERNATIONAL, 2026, 卷号: 229, 页码: 13
作者:
Suo, Qishan
;
Yue, Yang
;
Wang, Jing
;
Wu, Ning
;
Geng, Lihua
  |  
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  |  
Discovery of novel and potent harringtonine derivative P2 via systematic structure-activity Optimization: Semi-Synthesis, anti-leukemia activity, and mechanism study
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 305, 页码: 23
作者:
Xu, Zhongli
;
Shen, Shuting
;
Ding, Xinyu
;
Wang, Xiaoyu
;
Zhang, Dejin
  |  
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  |  
Synthesis, Biological Evaluation, and Computational Studies of Phenolic
N
-Acetylglucosamine Glycosides as α-Glucosidase Inhibitors
期刊论文
OAI收割
MARINE DRUGS, 2026, 卷号: 24, 期号: 2, 页码: 18
作者:
Wang, Wenjie
;
Gao, Kun
;
Li, Guantian
;
Wang, Zongji
;
Li, Kecheng
  |  
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  |  
CSF1R inhibitor C19 for glioma immunotherapy enabled by brain-targeting liposomal delivery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 11
作者:
Song, Wen-qin
;
Wu, Yue-qian
;
Zhu, Quan-feng
;
Xia, Xing-ping
;
Wang, Rui
  |  
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  |  
A patent review of KDM4 histone demethylase inhibitors (2014-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2026, 页码: 17
作者:
Yang, Xiaolong
;
Han, Yuyan
;
Yu, Lei
;
Xu, Shilin
  |  
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  |  
Novel thieno[2,3-b]pyridine derivatives protect islet through DRAK2 kinase inhibition
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 18
作者:
Lian, Kaiyue
;
Li, Ruihan
;
Lu, Yuting
;
Song, Gaolei
;
Zhang, Xinwen
  |  
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  |  
Discovery of 2-tetrahydroisoquinoline substituted quinazoline derivatives as lysine methyltransferase G9a inhibitors with in vivo antitumor efficacy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 300, 页码: 15
作者:
Shao, Mengjie
;
Gao, Lixin
;
Xu, Jiahui
;
Zhu, Lingfeng
;
Lu, Yiting
  |  
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  |  
Pharmacokinetics, mass balance, and metabolism of [
14
C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:
Gao, Lei
;
Ma, Sheng
;
Yan, Shu
;
Zhang, Hua
;
Tian, Ling
  |  
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  |