中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共1467条,第1-10条 帮助

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Design, synthesis and biological evaluation of novel pyrrolo[1,2-b]pyridazin-2(1H)-ones as selective PARP1 inhibitors for cancer therapy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 16
作者:  
He, Qiaolin;  He, Jing;  Huan, Xiajuan;  Song, Shanshan;  Zhang, Xiaofei
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Discovery and optimization of Menin-MLL inhibitors targeting acute myeloid leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 15
作者:  
Xiao, Qitao;  Wang, Yuxian;  Shen, Zheyuan;  Mo, Jun;  Li, Cong
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Discovery and molecular mechanism of a novel antihypertensive peptide from Chlamydomonas reinhardtii based on molecular docking, molecular dynamics simulation, in vitro, and in vivo analysis 期刊论文  OAI收割
FOOD RESEARCH INTERNATIONAL, 2026, 卷号: 229, 页码: 13
作者:  
Suo, Qishan;  Yue, Yang;  Wang, Jing;  Wu, Ning;  Geng, Lihua
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Discovery of novel and potent harringtonine derivative P2 via systematic structure-activity Optimization: Semi-Synthesis, anti-leukemia activity, and mechanism study 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 305, 页码: 23
作者:  
Xu, Zhongli;  Shen, Shuting;  Ding, Xinyu;  Wang, Xiaoyu;  Zhang, Dejin
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Synthesis, Biological Evaluation, and Computational Studies of Phenolic N-Acetylglucosamine Glycosides as α-Glucosidase Inhibitors 期刊论文  OAI收割
MARINE DRUGS, 2026, 卷号: 24, 期号: 2, 页码: 18
作者:  
Wang, Wenjie;  Gao, Kun;  Li, Guantian;  Wang, Zongji;  Li, Kecheng
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CSF1R inhibitor C19 for glioma immunotherapy enabled by brain-targeting liposomal delivery 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 11
作者:  
Song, Wen-qin;  Wu, Yue-qian;  Zhu, Quan-feng;  Xia, Xing-ping;  Wang, Rui
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A patent review of KDM4 histone demethylase inhibitors (2014-present) 期刊论文  OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2026, 页码: 17
作者:  
Yang, Xiaolong;  Han, Yuyan;  Yu, Lei;  Xu, Shilin
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Novel thieno[2,3-b]pyridine derivatives protect islet through DRAK2 kinase inhibition 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 18
作者:  
Lian, Kaiyue;  Li, Ruihan;  Lu, Yuting;  Song, Gaolei;  Zhang, Xinwen
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Discovery of 2-tetrahydroisoquinoline substituted quinazoline derivatives as lysine methyltransferase G9a inhibitors with in vivo antitumor efficacy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 300, 页码: 15
作者:  
Shao, Mengjie;  Gao, Lixin;  Xu, Jiahui;  Zhu, Lingfeng;  Lu, Yiting
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Pharmacokinetics, mass balance, and metabolism of [14C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans 期刊论文  OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:  
Gao, Lei;  Ma, Sheng;  Yan, Shu;  Zhang, Hua;  Tian, Ling
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