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浏览/检索结果: 共1424条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Pharmacokinetics, mass balance, and metabolism of [14C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans 期刊论文  OAI收割 CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12 作者:  Gao, Lei;  Ma, Sheng;  Yan, Shu;  Zhang, Hua;  Tian, Ling   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/07/25 FCN-437c  CDK4/6 inhibitor  Mass balance  Radiopharmacokinetics  Drug metabolism   Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23 作者:  Yuan, Haibin;  Gao, Yue;  Wang, Peipei;  Dong, Xiaowu;  Li, Jia   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 AML  FLT3/IRAK4 inhibitor  Pyrrolo [2,3-d] pyrimidine  Acquired resistance  Adaptive resistance   Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14 作者:  Tian, Lina;  Xiao, Jian;  Zeng, Yanping;  Li, Yangsha;  Wei, Aihuan   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 CDK9  EZH2  Dual target inhibitor  DLBCL   Design and structural optimization of novel SOS1 inhibitors in KRAS-driven cancers 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 125, 页码: 8 作者:  Chen, Yating;  Liu, Qiupei;  Meng, Xianghui;  Cao, Wenxu;  Duo, Lihui   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/08/20 SOS1 inhibitor  KRAS mutation  SOS1-KRAS interaction  Resistance   Discovery of novel Ebola entry inhibitors with 1,2,3,4-tetrahydroisoquinoline-3-carboxamide based on (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 123, 页码: 4 作者:  Lin, Junzhen;  Xiao, Fuling;  Han, Sheng;  Hu, Youhong;  Zuo, Jianping   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/06/23 Ebola virus entry inhibitor  Tetrahydroisoquinoline   Integrative Proteomics and Histone PTMomics Study on Anti-TNBC Effect of JIB-04 期刊论文  OAI收割 JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2025, 页码: 12 作者:  Tao, Shengna;  Guo, Jingli;  Zhang, Jingdan;  Zhang, Mingya;  Wang, Zhe   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/08/20 Proteomics  histone PTMomics  epigenetic inhibitor  JIB-04  TNBC   Covalent sortase A inhibitor, α, β-unsaturated aldehydes, prevents Staphylococcus aureus infection 期刊论文  OAI收割 MICROBIAL PATHOGENESIS, 2025, 卷号: 204, 页码: 12 作者:  Wang, Jianchao;  He, Yuan;  Chu, Chenliang;  Wu, Ziqi;  Zhang, Ting   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/06/23 Sortase A  Covalent inhibitor  alpha  beta-unsaturated aldehydes  Anti-virulence therapy  Staphylococcus aureus   Research progress on critical viral protease inhibitors for coronaviruses and enteroviruses 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 122, 页码: 19 作者:  Hu, Shulei;  Zhong, Qiuyu;  Xie, Xiong;  Zhang, Shurui;  Wang, Jinlin   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/05/27 Innate immunity response  SARS-CoV-2 3CLpro  PLpro  EV71 3Cpro  2Apro  Viral protease inhibitor   Nanohydroxyapatite-Stabilized Pickering-Emulsion-Incorporated Hydrogel Prevents Postoperative Osteosarcoma Recurrence and Promotes Bone Repair 期刊论文  OAI收割 NANO LETTERS, 2025, 卷号: 25, 期号: 26, 页码: 10487-10496 作者:  Zhang, Yi;  Wang, Yuewei;  Zhang, Xiaofei;  Yue, Lixia;  Yang, Lu   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 osteosarcoma  injectable hydrogel  nanohydroxyapatite  Pickering emulsion  RANKL inhibitor  bone regeneration   Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 160, 页码: 16 作者:  Chen, Sumeng;  Huang, Jindi;  Zhang, Shipeng;  Zheng, Xinni;  Chen, Hongming   |  收藏  |  浏览/下载：16/0  |  提交时间：2025/06/23 CDK9  Inhibitor  Acute myeloid leukemia  Binding mode  Cellular mechanism