中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [27]
成都生物研究所 [10]
水生生物研究所 [5]
昆明植物研究所 [3]
上海生物化学与细胞生... [3]
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OAI收割 [59]
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期刊论文 [55]
学位论文 [4]
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2025 [2]
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2020 [3]
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浏览/检索结果:
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A glycogen derived from sea urchin-
Strongylocentyotus internedius
shifts macrophages to the M1 phenotype and enhances the anti-pancreatic cancer activity of gemcitabine
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2025, 卷号: 16, 页码: 12
作者:
Deng, Zhenzhen
;
Yu, Haoyu
;
Wu, Ning
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/09/26
glycogen
tumor microenvironment
JAK
STAT signaling pathway
gemcitabine
macrophages
UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19
作者:
Wang, Li
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/06/23
UBE4B
BET inhibitors
Resistance
KLHL22
JAK2
Tofacitinib prevents depressive-like behaviors through decreased hippocampal microgliosis and increased BDNF levels in both LPS-induced and CSDS-induced mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Gao, Ya-nan
;
Pan, Kai-jun
;
Zhang, Yong-mei
;
Qi, Ying-bei
;
Chen, Wen-gang
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2024/11/05
tofacitinib
depression
JAK-STAT pathway
microgliosis
synaptic defects
ABBV-744 alleviates LPS-induced neuroinflammation via regulation of BATF2-IRF4-STAT1/3/5 axis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Wang, Le-le
;
Wang, Huan
;
Lin, Si-jin
;
Xu, Xing-yu
;
Hu, Wen-juan
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2024/07/12
microglial inflammation
BD2
ABBV-744
BATF2
IRF4
JAK/STAT
JE-133 Suppresses LPS-Induced Neuroinflammation Associated with the Regulation of JAK/STAT and Nrf2 Signaling Pathways
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 2, 页码: 258-267
作者:
Tao, Lingxue
;
Yu, Weichen
;
Liu, Ziyi
;
Zhao, Danfeng
;
Lin, Sijin
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2024/02/27
neuroinflammation
microglia
LPS
JAK/STAT
Nrf2
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
Integrating serum pharmacochemistry and network pharmacology to reveal the active constituents and mechanism of Corydalis Rhizoma in treating Alzheimer's disease
期刊论文
OAI收割
FRONTIERS IN AGING NEUROSCIENCE, 2023, 卷号: 15, 页码: 20
作者:
Lyu, Yan
;
Wang, Yu
;
Guo, Jianyou
;
Wang, Yuqing
;
Lu, Yifan
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2024/01/02
Corydalis Rhizoma
Alzheimer's disease
serum pharmacochemistry
network pharmacological
neuroinflammation
polarization type of BV2
JAK2/STAT3
A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 2, 页码: 215
作者:
Zhang Bibo
;
Li Bo
;
Xie Yongsheng
;
Chang Shuaikang
;
Xu Zhijian
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2023/07/18
DCZ0358
apoptosis
cell cycle arrest
multiple myeloma
JAK2/STAT3 pathway
Total flavones from Sceptridium ternatum alleviate pulmonary hypertension through inhibiting the proliferation of vascular endothelial cells
期刊论文
OAI收割
ANNALS OF TRANSLATIONAL MEDICINE, 2022
作者:
Li, Qinglin
;
Xin, Wenxiu
;
Ding, Haiyin
;
Zhang, Yiwen
;
Zheng, Xiaowei
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/12/23
Total flavones
pulmonary hypertension (PH)
HIF-?
JAK2-STAT3
Sceptridium ternatum
Design, synthesis and structure-activity relationship studies of pyrido [2,3-d]pyrimidin-7-ones as potent Janus Kinase 3 (JAK3) covalent inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 64, 页码: 128680
作者:
Su, Wenhong
;
Chen, Zhiwen
;
Liu, Meiying
;
He, Rui
;
Liu, Chaoyi
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2024/03/21
JAK3
Covalent inhibitor
Anti-cancer activity
Selectivity