中国科学院机构知识库网格系统: 检索

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	Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195 作者: Hu, Jianping; Wang, Yingqing; Li, Yanlian; Xu, Lin; Cao, Danyan \| 收藏 \| 浏览/下载：51/0 \| 提交时间：2019/01/08 BRD4 inhibitor Kinase BI-2536 Dihydroquinoxalin-2(1H)-one
	Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents 期刊论文 OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372 作者: Zhang Lan; Deng Xinshan; Wu Jiaofeng; Meng Guangpeng; Liu Congchong \| 收藏 \| 浏览/下载：61/0 \| 提交时间：2021/02/02 MOLECULAR TARGETED DRUGS TYROSINE KINASE CANCER-CELLS EGFR RESISTANCE POTENT DISCOVERY NSCLC Anticancer activity Epidemal growth factor receptor(EGFR) inhibitor N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative
	Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents 期刊论文 OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372 作者: Zhang Lan; Deng Xinshan; Wu Jiaofeng; Meng Guangpeng; Liu Congchong \| 收藏 \| 浏览/下载：59/0 \| 提交时间：2021/02/02 MOLECULAR TARGETED DRUGS TYROSINE KINASE CANCER-CELLS EGFR RESISTANCE POTENT DISCOVERY NSCLC Anticancer activity Epidemal growth factor receptor(EGFR) inhibitor N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative
	Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl) benzamides as novel RET kinase inhibitors 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 23, 页码: 5679-5684 作者: Han, Mei; Li, Shan; Ai, Jing; Sheng, Rong; Hu, Yongzhou \| 收藏 \| 浏览/下载：29/0 \| 提交时间：2019/01/08 RET kinase inhibitor 1,2,4-Oxadiazole Anti-cancer therapy
	Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2) 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 11, 页码: 2600-2604 作者: Li, Lei; Liu, Feifei; Jin, Nan; Tang, Shuai; Chen, Zhuxi \| 收藏 \| 浏览/下载：17/0 \| 提交时间：2019/01/08 ERK1/2 kinase inhibitor Indazole amide Structure based drug design
	The crossregulation between ERK and PI3K signaling pathways determines the tumoricidal efficacy of MEK inhibitor 期刊论文 OAI收割 JOURNAL OF MOLECULAR CELL BIOLOGY, 2012, 卷号: 4 - \| 收藏 \| 浏览/下载：27/0 \| 提交时间：2020/10/26 KINASE KINASE-1/2 INHIBITOR PHOSPHOINOSITIDE 3-KINASE-GAMMA ADVANCED CANCERS LUNG-CANCER CELL LUNG PHASE-II RESISTANCE ROBUSTNESS ACTIVATION MUTATIONS systems biology mathematical model ERK pathway PI3K pathway MEK inhibitor resistance robustness biochemical control analysis
	asesquiterpenequinonedysidinefromthespongedysideavillosaactivatestheinsulinpathwaythroughinhibitionofptpases 期刊论文 OAI收割 actapharmacologicasinica, 2009, 卷号: 30, 期号: 3, 页码: 333 作者: Yu ZHANG; Yan LI; Yuewei GUO; Hualiang JIANG; Xu SHEN \| 收藏 \| 浏览/下载：18/0 \| 提交时间：2020/07/01 TYROSINE-PHOSPHATASE 1B STIMULATES GLUCOSE-UPTAKE PROTEIN-KINASE INHIBITOR 3T3-L1 ADIPOCYTES SELECTIVE INHIBITORS GLUT4 TRANSLOCATION PHOSPHOLIPASE A(2) PLASMA-MEMBRANE LEPTIN ACTION SENSITIVITY sesquiterpene quinone dysidine PTP1B inhibitor insulin
	Antitumor activity of a new N-substituted thiourea derivative, an EGFR signaling-targeted inhibitor against a panel of human lung cancer cell lines 期刊论文 OAI收割 CHEMOTHERAPY, 2008, 卷号: 54, 期号: 6, 页码: 463-474 作者: Xiong, Xishan; Liu, Hong; Fu, Lili; Li, Lin; Li, Jian \| 收藏 \| 浏览/下载：40/0 \| 提交时间：2019/01/08 EGFR tyrosine kinase inhibitor non-small-cell lung cancer IC50 Erk1/2 AKT