中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
大连化学物理研究所 [16]
上海药物研究所 [7]
长春应用化学研究所 [3]
金属研究所 [2]
广州地球化学研究所 [1]
化学研究所 [1]
更多
采集方式
OAI收割 [33]
iSwitch采集 [1]
内容类型
期刊论文 [34]
发表日期
2025 [1]
2021 [1]
2020 [1]
2019 [2]
2017 [5]
2016 [3]
更多
学科主题
物理化学 [3]
Chemistry [2]
Biochemist... [1]
Chemistry,... [1]
Pharmacolo... [1]
Physics [1]
更多
筛选
浏览/检索结果:
共34条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
A comprehensive characterization biotransformation of chlorinated paraffin by human and carp liver microsomes via liquid chromatography-high-resolution mass spectrometry and screening algorithm
期刊论文
OAI收割
ENVIRONMENT INTERNATIONAL, 2025, 卷号: 195, 页码: 11
作者:
Chen, Liujun
;
Tang, Caiming
;
Yu, Zhiqiang
;
Zeng, Yanhong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/03
Chlorinated Paraffins
Biotransformation
Liver microsomes
Metabolites
Toxicity assessment
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
OAI收割
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes
期刊论文
OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7
作者:
Li, Hao-Jv
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Yao, Chang-Liang
;
Wang, Meng-Yuan
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
Uncaria rhynchophylla
Indole alkaloids
Mass defect filter
Time-staggered targeted ion lists
Metabolite identification
Liver microsomes
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
iSwitch采集
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Comparative metabolism of DDAO benzoate in liver microsomes from various species
期刊论文
OAI收割
TOXICOLOGY IN VITRO, 2017, 卷号: 44, 页码: 280-286
作者:
Ge, Guang-Bo
;
Ma, Hong-Ying
;
Yang, Jia-Da
;
Hou, Jie
;
Zou, Li-Wei
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2017/12/19
DDAB hydrolysis
Carboxylesterase 2 (CE2)
Species differences
Liver microsomes
Comparative metabolism of DDAO benzoate in liver microsomes from various species
期刊论文
OAI收割
TOXICOLOGY IN VITRO, 2017, 卷号: 44, 页码: 280-286
作者:
Ma, Hong-Ying
;
Yang, Jia-Da
;
Hou, Jie
;
Zou, Li-Wei
;
Jin, Qiang
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2017/12/19
DDAB hydrolysis
Carboxylesterase 2 (CE2)
Species differences
Liver microsomes
Metabolic profiling of five flavonoids from Dragon's Blood in human liver microsomes using high-performance liquid chromatography coupled with high resolution mass spectrometry
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2017, 卷号: 1052, 页码: 91-102
作者:
Li, Yujuan
;
Zhang, Yushi
;
Wang, Rui
;
Wei, Lizhong
;
Deng, Yulin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2018/04/10
Dragon's Blood
Human Liver Microsomes
Hplc-hr-ms
Metabolites
Identification of human UDP-glucuronosyltransferase isoforms involved in the isofraxidin glucuronidation and assessment of the species differences of the reaction
期刊论文
OAI收割
FITOTERAPIA, 2017, 卷号: 117, 页码: 118-125
作者:
Meng, Fanxing
;
Li, Yan
;
He, Guiyuan
;
Ge, Guangbo
;
Liu, Shumin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/06/20
Isofraxidin
Udp-glucuronosyltransferases (Ugts)
Human Liver Microsomes (Hlm)
Human Intestinal Microsomes (Him)
Species Differences
Metabolic profiling of myrislignan by UPLC-ESI-QTOFMS-based metabolomics
期刊论文
OAI收割
RSC ADVANCES, 2017, 卷号: 7, 期号: 64, 页码: 40131-40140
作者:
Yang, Xiao-Nan
;
Lv, Qian-Qian
;
Zhao, Qi
;
Li, Xin-Mei
;
Yan, Dong-Mei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2017/10/23
Myristica-fragrans
In-vitro
Liver-microsomes
Neolignans
Extract
Lignans
Pharmacokinetics
Identification
Noscapine
Reveals