中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
大连化学物理研究所 [1]
昆明植物研究所 [1]
生态环境研究中心 [1]
合肥物质科学研究院 [1]
长春应用化学研究所 [1]
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采集方式
OAI收割 [17]
内容类型
期刊论文 [17]
发表日期
2022 [1]
2020 [1]
2019 [1]
2018 [1]
2017 [4]
2014 [2]
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学科主题
Chemistry [2]
Biochemist... [1]
Endocrinol... [1]
Medicinal [1]
Organic [1]
Pharmacolo... [1]
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浏览/检索结果:
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Inhibition of STAT3 Signaling Pathway by Terphenyllin Suppresses Growth and Metastasis of Gastric Cancer
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Yu, Dehua
;
Qi, Simin
;
Guan, Xiaoqing
;
Yu, Wenkai
;
Yu, Xuefei
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2022/12/23
STAT3
inhibitor
natural product
gastric cancer
terphenyllin
Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 423-431
作者:
Guo, Wei
;
Yao, Sheng
;
Sun, Pu
;
Yang, Tian-biao
;
Tang, Chun-ping
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/07/01
indoleamine 2
3-dioxygenase 1 inhibitor
natural product library
high-throughput fluorescence-based screening
Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases
期刊论文
OAI收割
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312
作者:
Liu, Man
;
Xiao, Cheng-qian
;
Sun, Ming-wei
;
Tan, Min-jia
;
Hu, Li-hong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
covalent interaction
IKK inhibitor
JAK inhibitor
natural compound
Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity
期刊论文
OAI收割
MARINE DRUGS, 2018, 卷号: 16, 期号: 3
作者:
Liu, Jin
;
Chen, Yu
;
Li, Jing-Ya
;
Luo, Cheng
;
Li, Jia
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
phidianidine
marine natural products
PTP1B inhibitor
specific selectivity
docking analysis
Function Oriented Synthesis
structure-activity relationship
Cycloalkane analogues of sinefungin as EHMT1/2 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4579-4594
作者:
Liu, Qing
;
Cai, Xiaoqing
;
Yang, Dehua
;
Chen, Yi
;
Wang, Yafang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Methyltransferase inhibitor
Cycloalkyl substituted analogue
Natural product
Sinefungin
5-Alkylpyrrole-2-carboxaldehyde derivatives from the Chinese sponge Mycale lissochela and their PTP1B inhibitory activities
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 6, 页码: 1190-1193
作者:
Xue, Duo-Qing
;
Liu, Hai-Li
;
Chen, Si-Han
;
Mollo, Ernesto
;
Gavagnin, Margherita
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
5-Alkylpyrrole-2-carboxaldehyde
Sponge
Mycale lissochela
PTP1B inhibitor
Marine natural product
Identification of Epigallocatechin-3-Gallate as an Inhibitor of Phosphoglycerate Mutase 1
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Li, Xiaoguang
;
Tang, Shuai
;
Wang, Qian-Qian
;
Leung, Elaine L. -H.
;
Jin, Hongyue
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
phosphoglycerate mutase 1 (PGAM1)
inhibitor
cancer metabolism
natural products
anticancer activity
Influence of natural zeolite and nitrification inhibitor on organics degradation and nitrogen transformation during sludge composting
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2017, 卷号: 24, 期号: 10, 页码: 9122-9122
作者:
Tong, Juan
;
Qi, Lu
;
Wei, Yuansong
;
Zhang, Junya
;
Sui, Qianwen
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2017/04/05
Sewage Sludge
Composting
Natural Zeolite
Nitrification Inhibitor ( Ni)
Nitrogen Transformation Functional Genes
3
4-dimethylpyrazole Phosphate (Dmpp)
Discovery of a novel inhibitor of NAD(P)(+)-dependent malic enzyme (ME2) by high-throughput screening
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 674-684
作者:
Wen, Yi
;
Xu, Lei
;
Chen, Fang-lei
;
Gao, Jing
;
Li, Jing-ya
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
malic enzyme
ME2
inhibitor
natural product
NPD389
high-throughput screening
structure-activity relationship
enzyme kinetics
thermal shift assay
Discovery of a novel inhibitor of NAD(P)~+-dependent malic enzyme (ME2) by high-throughput screening
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2014, 卷号: 35, 期号: 5, 页码: 674
作者:
Wen Yi
;
Xu Lei
;
Chen Fanglei
;
Gao Jing
;
Li Jingya
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
THERMAL SHIFT ASSAYS
STATISTICAL PARAMETER
QUALITY-CONTROL
DRUG DISCOVERY
RNAI SCREENS
PROGRESSION
MECHANISM
HIT
ATP
malic enzyme
ME2
inhibitor
natural product
NPD389
high-throughput screening
structure-activity relationship
enzyme kinetics
thermal shift assay