中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
长春应用化学研究所 [3]
化学研究所 [1]
中国科学院大学 [1]
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OAI收割 [12]
iSwitch采集 [1]
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期刊论文 [12]
会议论文 [1]
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2024 [1]
2022 [2]
2020 [1]
2018 [1]
2016 [1]
2015 [1]
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Oral peptide therapeutics for diabetes treatment: State-of-the-art and future perspectives
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 5, 页码: 2006-2025
作者:
Ding, Bingwen
;
Zhu, Zhu
;
Guo, Cong
;
Li, Jiaxin
;
Gan, Yong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/09/26
Oral peptides
Diabetes
Delivery platforms
Insulin
Glucagon-like peptide-1
Biodistribution
Biological barriers
Targeted delivery
The complexation of insulin with sodium N-[8-(2-hydroxybenzoyl)amino]-caprylate for enhanced oral delivery: Effects of concentration, ratio, and pH
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2022, 卷号: 33, 期号: 4, 页码: 1889-1894
作者:
Weng, Huixian
;
Hu, Lefei
;
Hu, Lei
;
Zhou, Yihan
;
Wang, Aohua
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/08/16
Oral insulin delivery
Permeation enhancer
SNAC
Absorption mechanism
Molecular interaction
The upregulated intestinal folate transporters direct the uptake of ligand-modified nanoparticles for enhanced oral insulin delivery
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 3, 页码: 1460-1472
作者:
Li, Jingyi
;
Zhang, Yaqi
;
Yu, Miaorong
;
Wang, Aohua
;
Qiu, Yu
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/06/15
Ligand-modified nanoparticles
Transporter
Proton-coupled folate transporter
Expression level
Endocytosis
Intracellular trafficking
Diabetes
Oral insulin delivery
Liver-Target and Glucose-Responsive Polymersomes toward Mimicking Endogenous Insulin Secretion with Improved Hepatic Glucose Utilization
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 15
作者:
  |  
收藏
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浏览/下载:58/0
  |  
提交时间:2020/07/01
glucose responsive
insulin secretion
liver target
oral drug delivery
polymersomes
Functional nanoparticles exploit the bile acid pathway to overcome multiple barriers of the intestinal epithelium for oral insulin delivery
期刊论文
OAI收割
BIOMATERIALS, 2018, 卷号: 151, 页码: 13-23
作者:
Fan, Weiwei
;
Xia, Dengning
;
Zhu, Quanlei
;
Li, Xiuying
;
He, Shufang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Oral delivery
Insulin
Functional nanoparticles
Bile acid pathway
Intestinal epithelium
Endolysosomal escape
Challenges and strategies of oral insulin delivery
会议论文
OAI收割
作者:
Gan Y(甘勇)
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
oral
Challenges and strategies of oral insulin delivery
Competitive binding-accelerated insulin release from a polypeptide nanogel for potential therapy of diabetes
期刊论文
OAI收割
polymer chemistry, 2015, 卷号: 6, 期号: 20, 页码: 3807-3815
作者:
Zhao,Li
;
Xiao,Chunsheng
;
Ding,Jianxun
;
Zhuang,Xiuli
;
Gai,Guangqing
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2016/05/06
RESPONSIVE CONTROLLED-RELEASE
REGULATED DRUG-DELIVERY
PHENYLBORONIC ACID
MESOPOROUS SILICA
PHYSIOLOGICAL PH
IN-VIVO
TRIGGERED RELEASE
GLUCOSE-OXIDASE
CONCANAVALIN-A
ORAL INSULIN
Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles
期刊论文
OAI收割
BIOMATERIALS, 2013, 卷号: 34, 期号: 37, 页码: 9678-9687
作者:
Li, Xiuying
;
Guo, Shiyan
;
Zhu, Chunliu
;
Zhu, Quanlei
;
Gan, Yong
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Oral protein delivery
Core shell corona
Insulin
Mucus penetrating particles
Cellular uptake
Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous composites
期刊论文
OAI收割
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING, 2013, 卷号: 7, 期号: 1, 页码: 9-19
作者:
He, Huining
;
Ye, Junxiao
;
Sheng, Jianyong
;
Wang, Jianxin
;
Huang, Yongzhuo
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
insulin
cell penetrating peptide
mucoadhesive composites
oral delivery
Preparation and Bioactivities of DhHP-6-loaded Biodegradable Polymeric Microspheres
期刊论文
OAI收割
chemical journal of chinese universities-chinese, 2013, 卷号: 34, 期号: 1, 页码: 236-241
Zhao TY
;
Zhao JP
;
Lei LY
;
Chen XG
;
Wang LC
;
Chen XS
;
Wang LP
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2014/04/20
DOUBLE-EMULSION METHOD
ORAL INSULIN DELIVERY
CHITOSAN MICROSPHERES
DRUG-RELEASE
PLGA
NANOPARTICLES
CELLS