中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
合肥物质科学研究院 [5]
成都生物研究所 [2]
海洋研究所 [2]
近代物理研究所 [2]
昆明植物研究所 [1]
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OAI收割 [38]
内容类型
期刊论文 [36]
会议论文 [1]
学位论文 [1]
发表日期
2024 [1]
2023 [4]
2022 [6]
2021 [5]
2020 [5]
2019 [3]
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学科主题
天然产物研究 [2]
Biochemist... [1]
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浏览/检索结果:
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Quinazoline-2,4
(1 H
,
3 H
)-dione Scaffold for development of a novel PARP-targeting PET probe for tumor imaging
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 页码: 14
作者:
He, Chunfeng
;
Shi, Hui
;
Tan, Boyu
;
Jiang, Zhaoning
;
Cao, Rui
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/22
PARP
Oncology
Quinazoline-2,4(1H,3H)-dione
PET/CT
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Advancements and Obstacles of PARP Inhibitors in Gastric Cancer
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 19
作者:
Chen, Hongjie
;
Hu, Yangchan
;
Zhuang, Zirui
;
Wang, Dingyi
;
Ye, Zu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/12/19
gastric cancer
DNA damage repair
PARP inhibitor
cancer therapy
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Combined inhibition of PARP and ATR synergistically potentiates the antitumor activity of HER2-targeting antibody-drug conjugate in HER2-positive cancers
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 卷号: 13, 期号: 1, 页码: 161-+
作者:
Li, Yongpeng
;
Li, Lin
;
Fu, Haoyu
;
Yao, Qing
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Antibody-drug conjugate
DS-8201
PARP
ATR
synergy
DNA damage
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-Zhen
;
Ma, Li-Ying
;
Zhang, Zong-Hui
;
Wang, Xiao-Lin
;
Hua, Jing-Han
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/12/22
small-cell lung cancer
H3
3
PARP1
PARP inhibitor
darinaparsin
combination treatment
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574
作者:
Kayumov, Muzaffar
;
Jia, Li
;
Pardaev, Azizbek
;
Song, Shan-Shan
;
Mirzaakhmedov, Sharafitdin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/03/21
PARP1
Olaparib
Alantolactone
Syntheticlethality
BRCA1/2mutant
Vanguard is a Glucose Deprivation-Responsive Long Non-Coding RNA Essential for Chromatin Remodeling-Reliant DNA Repair
期刊论文
OAI收割
ADVANCED SCIENCE, 2022
作者:
Zhang, Ben
;
Thorne, Rick Francis
;
Zhang, Pengfei
;
Wu, Mian
;
Liu, Lianxin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/12/23
genomic stability
HMGB1
long non-coding RNAs
PARP inhibitors
Vanguard
Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial
期刊论文
OAI收割
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022
作者:
Liu, Jihong
;
Yin, Rutie
;
Wu, Lingying
;
Zhu, Jianqing
;
Lou, Ge
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2022/05/05
BRCA mutation
China
olaparib
ovarian cancer
PARP inhibitor
Metabolite profiles and mass balance of fuzuloparib, a novel poly (ADP-ribose) polymerase inhibitor, in subjects with advanced solid cancers
期刊论文
OAI收割
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2022, 页码: 14
作者:
Bian, Yicong
;
Meng, Jian
;
Ma, Sheng
;
Li, Guangze
;
Wang, Yuya
  |  
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2022/06/15
fuzuloparib
mass balance
metabolite profiles
PARP
pharmacokinetics