机构

• 上海药物研究所 [11]
• 合肥物质科学研究院 [2]
• 海洋研究所 [1]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2023 [3]
• 2022 [2]
• 2021 [2]
• 2020 [1]
• 2019 [2]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者:  Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong   |  收藏  |  浏览/下载：70/0  |  提交时间：2023/10/17 PARP1 inhibitor  Synthetic lethality  Drug resistance  Anticancer  Structure -activity relationship   Advancements and Obstacles of PARP Inhibitors in Gastric Cancer 期刊论文  OAI收割 CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 19 作者:  Chen, Hongjie;  Hu, Yangchan;  Zhuang, Zirui;  Wang, Dingyi;  Ye, Zu   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/12/19 gastric cancer  DNA damage repair  PARP inhibitor  cancer therapy   Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：51/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者:  Cao, Guo-Zhen;  Ma, Li-Ying;  Zhang, Zong-Hui;  Wang, Xiao-Lin;  Hua, Jing-Han   |  收藏  |  浏览/下载：47/0  |  提交时间：2022/12/22 small-cell lung cancer  H3  3  PARP1  PARP inhibitor  darinaparsin  combination treatment   Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial 期刊论文  OAI收割 ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022 作者:  Liu, Jihong;  Yin, Rutie;  Wu, Lingying;  Zhu, Jianqing;  Lou, Ge   |  收藏  |  浏览/下载：64/0  |  提交时间：2022/05/05 BRCA mutation  China  olaparib  ovarian cancer  PARP inhibitor   Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers 期刊论文  OAI收割 INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9 作者:  Li, Meng-Zhu;  Meng, Tao;  Song, Shan-Shan;  Bao, Xu-Bin;  Ma, Lan-Ping   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/05/24 G-quadruplex stabilizer  MTR-106  BRCA-deficiency  PARP inhibitor  DNA damage   Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells 期刊论文  OAI收割 FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10 作者:  Wu, Xiaochen;  Li, Qiqi;  Zhang, Fan;  Wang, Lijun;  Wang, Jun   |  收藏  |  浏览/下载：40/0  |  提交时间：2021/04/21 PARP inhibitor  BRCA  Pancreatic cancer   Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors 期刊论文  OAI收割 CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+ 作者:  Li, Huiping;  Liu, Rongrui;  Shao, Bin;  Ran, Ran;  Song, Guohong   |  收藏  |  浏览/下载：47/0  |  提交时间：2020/12/24 Phase I  PARP inhibitor (fluzoparib)  solid tumor  pharmacokinetics  safety  antitumor activity   USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells 期刊论文  OAI收割 CANCER MEDICINE, 2019, 卷号: 8, 期号: 15, 页码: 6730-6740 作者:  Lu, Qin;  Zhang, Fang-Lin;  Lu, Da-Yun;  Shao, Zhi-Ming;  Li, Da-Qiang   |  收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 BRCA1  breast cancer  deubiquitinase  PARP inhibitor  USP9X   Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 714-727 作者:  Chen, Hua-Dong;  Chen, Chuan-Huizi;  Wang, Yu-Ting;  Guo, Ne;  Tian, Yu-Nan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/21 PARP1 inhibitor  PARP1-DNA binding  PARP1-DNA trapping  poly(ADP-ribose) polymerase activity  cytotoxicity