中国科学院机构知识库网格系统: 检索

浏览/检索结果: 共9条，第1-9条

帮助

条数/页：排序方式：
	Design, synthesis and biological evaluation of novel pyrrolo[1,2-b]pyridazin-2(1H)-ones as selective PARP1 inhibitors for cancer therapy 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 16 作者: He, Qiaolin; He, Jing; Huan, Xiajuan; Song, Shanshan; Zhang, Xiaofei \| 收藏 \|
	Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者: Wang, Pingyuan; Zhu, Wen-Ting; Wang, Yajing; Song, Shan-Shan; Xi, Yong \| 收藏 \|
	Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者: Cao, Guo-Zhen; Ma, Li-Ying; Zhang, Zong-Hui; Wang, Xiao-Lin; Hua, Jing-Han \| 收藏 \|
	Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574 作者: Kayumov, Muzaffar; Jia, Li; Pardaev, Azizbek; Song, Shan-Shan; Mirzaakhmedov, Sharafitdin \| 收藏 \|
	Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion 期刊论文 OAI收割 CANCER BIOLOGY & THERAPY, 2022, 页码: 14 作者: Guo, Ne; Li, Meng-Zhu; Wang, Li-Min; Chen, Hua-Dong \| 收藏 \|
	The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文 OAI收割 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39 作者: Ma, Liying; Bian, Xing; Lin, Wenchu \| 收藏 \|
	The MYC Paralog-PARP1 Axis as a Potential TherapeuticTarget in MYC Paralog-Activated Small Cell Lung Cancer 期刊论文 OAI收割 FRONTIERS IN ONCOLOGY, 2020, 卷号: 10 作者: Bian, Xing; Wang, Xiaolin; Zhang, Qiuyan; Ma, Liying; Cao, Guozhen \| 收藏 \|
	Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文 OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 714-727 作者: Chen, Hua-Dong; Chen, Chuan-Huizi; Wang, Yu-Ting; Guo, Ne; Tian, Yu-Nan \| 收藏 \|
	Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 389-403 作者: Chen, Xuxing; Huan, Xiajuan; Liu, Qiufeng; Wang, Yuqin; He, Qian \| 收藏 \|