中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
长春应用化学研究所 [38]
上海药物研究所 [17]
上海生物化学与细胞... [13]
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期刊论文 [190]
学位论文 [2]
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Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair
期刊论文
OAI收割
TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11
作者:
Chi, Shuaishuai
;
Wei, Fan
;
Li, Yangsha
;
Yu, Lei
;
Ma, Chuyao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/01/06
CDK4
BRD4
Breast cancer
Protein stability
DNA damage
Transcriptomic Landscape Analysis Reveals a Persistent DNA Damage Response in Metabolic Dysfunction-associated Steatohepatitis Post-dietary Intervention
期刊论文
OAI收割
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY, 2024, 页码: 15
作者:
Zou, Zi-Yuan
;
Ren, Tian-Yi
;
Jiao, Ting-Ying
;
Wang, Meng-Yu
;
Huang, Lei-Jie
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/09/26
Apoptosis
DNA Damage
Metabolic dysfunction-associated stea- totic liver disease
RNA-Seq
Tumor suppressor protein P53
Western Diets
Dynamics of imprinted genes and their epigenetic mechanisms in castor bean seed with persistent endosperm
期刊论文
OAI收割
NEW PHYTOLOGIST, 2023, 卷号: 240, 期号: 5, 页码: 1868-1882
作者:
Han,Bing
;
Li,Yelan
;
Wu,Di
;
Li,De-Zhu
;
Liu,Aizhong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/07/10
castor bean
DNA methylation
endosperm
epigenetic mechanisms
genomic imprinting
histone modifications
DNA METHYLATION
ARABIDOPSIS
EXPRESSION
EVOLUTION
PROTEIN
PLANTS
CONSERVATION
DEMETER
PHERES1
COAT
Memory Effect on the Survival of Deinococcus radiodurans after Exposure in Near Space
期刊论文
OAI收割
MICROBIOLOGY SPECTRUM, 2023, 卷号: 11, 期号: 2
作者:
Chen, Yining
;
Zhang, Qing
;
Wang, Deyu
;
Shu, Yao-Gen
;
Shi, Hualin
  |  
收藏
  |  
浏览/下载:154/0
  |  
提交时间:2023/12/07
UV-C RESISTANCE
ESCHERICHIA-COLI
DNA-DAMAGE
HOMOLOGOUS RECOMBINATION
INTERPLANETARY TRANSFER
RADIATION-RESISTANCE
STRESS-RESPONSE
PROTEIN DAMAGE
GROWTH-RATE
REPAIR
Single-base methylome analysis reveals dynamic changes of genome-wide DNA methylation associated with rapid stem growth of woody bamboos
期刊论文
OAI收割
PLANTA, 2022, 卷号: 256, 期号: 3, 页码: 53
作者:
Niu, Liang-Zhong
;
Xu, Wei
;
Ma, Peng-Fei
;
Guo, Zhen-Hua
;
Li, De-Zhu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/04/30
DNA methylation
Gene expression
Internode elongation
Jasmonic acid
Woody bamboos
PHENYLALANINE AMMONIA-LYASE
MOLECULAR CHARACTERIZATION
CYTOSINE METHYLTRANSFERASE
INTERNODE ELONGATION
TRANSCRIPTION FACTOR
H3 LYSINE-9
ARABIDOPSIS
EXPRESSION
DEMETHYLATION
PROTEIN
Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10, 页码: 16
作者:
Yan, Yi-lin
;
Huang, Zheng-nan
;
Zhu, Zhen
;
Cui, Yang-yan
;
Li, Mei-qian
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
ten-eleven translocation 1 (TET1)
DNA methylation
bladder cancer
vitamin C
adherens junction-associated protein 1 (AJAP1)
Characterization of functional transposable element enhancers in acute myeloid leukemia
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2020, 卷号: 63, 期号: 5, 页码: 675-687
作者:
Zeng, Yingying
;
Cao, Yaqiang
;
Liu, Denghui
;
Zhang, Xiaoli
;
Han, Jing-Dong J.
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/21
SET ENRICHMENT ANALYSIS
C-JUN
GENE
GENOME
CHROMATIN
EVOLUTION
MLL-AF9
PROTEIN
DNA
DIFFERENTIATION
Micromixers and their applications in kinetic analysis of biochemical reactions
期刊论文
OAI收割
TALANTA, 2019, 卷号: 205, 页码: 9
作者:
Liu, Chao
;
Li, Ying
;
Liu, Bi-Feng
  |  
收藏
  |  
浏览/下载:345/0
  |  
提交时间:2019/12/06
Micromixer
Fast mixing
Kinetics
Protein folding
DNA/RNA folding
Biomolecular interaction
Enzyme catalysis
Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 22, 页码: 8907-8917
作者:
Du, Wenlong
;
Dong, Qiang
;
Zhang, Zhuqiang
;
Liu, Baodong
;
Zhou, Ting
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/10/21
DNA demethylation
DNA methylation
gene regulation
epigenetics
protein-protein interaction
chromatin association
developmental pluripotency associated 3 (DPPA3)
FRAP assay
Stella
ubiquitin-like with PHD and RING finger domains 1 (UHRF1)