中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [31]
合肥物质科学研究院 [24]
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期刊论文 [101]
学位论文 [3]
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HDAC inhibitor GCJ-490A modulates tumor microenvironment and synergizes with PD-1 antibody against breast and lung cancers in syngeneic murine models
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13
作者:
Zhang, Wen-xin
;
He, Ting
;
Fang, Kun
;
Gao, Ying-lei
;
Sun, Yi-ming
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/12/04
HDAC inhibitor
GCJ-490A
tumor microenvironment
PD-1 antibody
CXCL7
Modulating G6PD/PGD to overcome FSP1/DHODH-mediated ferroptosis defence: A novel oridonin derivative suppresses liver cancer
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2025, 页码: 19
作者:
Ma, Chenhui
;
Han, Li
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
ferroptosis
FSP1 and DHODH
G6PD and PGD
liver cancer
oridonin
Cantharidin-Loaded Nanomedicine Modified with Amphiphilic Peptides Induce Immunogenic Cell Death to Enhance PD-1 Blockade
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2025, 卷号: 17, 期号: 29, 页码: 41571-41585
作者:
Tang, Yang
;
Jiang, Qun
;
Chen, Rongli
;
Wu, Siqi
;
Luo, Yichang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
cantharidin
amphiphilic peptide
immunogeniccell death
PD-1 blockade
tumor microenvironment
A Dendritic Cell-Nanogel Conjugate for Tumor-Draining Lymph Node-Specific PD-L1 Blockade
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 16
作者:
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/12/04
anti-PD-L1 antibody
dendritic cells
immunotherapy
tumor-derived lymph nodes
Bacterial Membrane Vesicles as Heteroantigen Reservoirs for Potentiated Colorectal Cancer Immunotherapy
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 26, 页码: 23760-23777
作者:
Liu, Chang
;
Yang, Canyu
;
Jiang, Xiuxian
;
Lu, Xiang
;
Huang, Xiaoyu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/08/20
immunotherapy
bacterial membrane vesicle
heteroantigen reservoir
PD-L1 siRNA
immune checkpointblockade
De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Geriatric Nutritional Risk Index is an effective prognostic predictor for metastatic/recurrent or unresectable esophageal cancer receiving immunotherapy
期刊论文
OAI收割
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2025, 卷号: 16, 期号: 1, 页码: 22
作者:
Wang, Bei
;
Wang, Zixuan
;
Xu, Chuanhai
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/05/27
Geriatric Nutritional Risk Index (GNRI)
esophageal squamous cell carcinoma (ESCC)
immune checkpoint inhibitors (ICIs)
programmed cell death ligand 1 (PD-L1)
Intratumoral lactic acid neutralization strategy for boosting chemoimmunotherapy using liposomal sodium bicarbonate
期刊论文
OAI收割
SCIENCE BULLETIN, 2024, 卷号: 69, 期号: 24, 页码: 3936-3948
作者:
Peng, Taoxing
;
Shao, Xinyue
;
Song, Wenqin
;
Xu, Weihua
;
Xiong, Wei
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2025/04/01
Sodium bicarbonate
Lactic acid neutralization
Tumor microenvironment normalization
Chemoimmunotherapy
PD-1 antibody
Ion-trapping barrier
Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual-Targeting BMI1 for Senescence Induction and CSN5 for PD-L1 Degradation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 21
作者:
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收藏
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浏览/下载:62/0
  |  
提交时间:2025/02/28
BMI1
colorectal cancer
CSN5
PD-L1
tumor cell senescence
Base-driven dehydrohalogenation coupled with catalytic hydrodehalogenation as a novel strategy for rapid dehalogenation of halogenated organic compounds containing aliphatic C-X bonds
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2024, 卷号: 12, 期号: 6, 页码: 11
作者:
Qin, Shuting
;
Wu, Chen
;
Ma, Xuanxuan
;
Liu, Sujing
;
Liu, Ying
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2025/01/10
Halogenated organic compounds (HOCs)
Base
Hydrodehalogenation (HDH)
Dehydrohalogenation (HDX)
Pd/C
(DDT)
1
1-trichloro-2
2-bis(4-chlorophenyl)ethane