中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Bicyclic polyprenylated acylphloroglucinol-related meroterpenoids as potent DRAK2 inhibitors from
Hypericum patulum
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 10
作者:
Huang, Jin-Chang
;
Jia, Xin-Yu
;
Lv, Yi-Fan
;
Xu, Hong-Hong
;
Han, Ming
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Hypericum patulum
Hypericaceae
Meroterpenoids
Hyperpatins A-H
Death-associated protein kinase-related
apoptosis-inducing kinase 2
Glucose-stimulated insulin secretion
A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 298, 页码: 13
作者:
Tong, Yongliang
;
Chen, Runqiu
;
Lu, Xinrong
;
Chen, Cuiying
;
Sun, Guiqin
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/01
Glycol-immunology
Nanobody-enzyme fusion protein
Sialic acid
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:
Hu, Linghao
;
Xu, Hesong
;
Xu, Ye
;
Chen, Haowen
;
Jiang, Hanrui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
NSD2
RE-IIBP
Targeted protein degradation
Multiple myeloma
A comprehensive review of current insights into the virulence factors of SARS-CoV-2
期刊论文
OAI收割
JOURNAL OF VIROLOGY, 2025, 页码: 22
作者:
Wang, Yi
;
Xia, Bingqing
;
Gao, Zhaobing
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
SARS-CoV-2
virulence factors
envelope protein
pathogenicity
Fibroblast activation protein peptide-targeted NIR-I/II fluorescence imaging for stable and functional detection of hepatocellular carcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 14
作者:
Lin, En
;
Song, Miaomiao
;
Wang, Bo
;
Shi, Xiaojing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Hepatocellular carcinoma
Cancer-associated fibroblasts
Fibroblast activation protein
Near-infrared fluorescence
Peptide-targeted fluorescence imaging
One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair
期刊论文
OAI收割
TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11
作者:
Chi, Shuaishuai
;
Wei, Fan
;
Li, Yangsha
;
Yu, Lei
;
Ma, Chuyao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/01/06
CDK4
BRD4
Breast cancer
Protein stability
DNA damage
Molecular and functional characterization of short peptidoglycan recognition proteins in Vesicomyidae clam
期刊论文
OAI收割
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2025, 卷号: 162, 页码: 16
作者:
Kong, Xue
;
Wang, Wei
;
Xia, Sunan
;
Zhi, Ying
;
Cai, Yuefeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/09
Vesicomyidae clam
Peptidoglycan recognition protein
Symbiosis
Cold seep zone
Enhanced Gut-to-Liver Oral Drug Delivery via Ligand-Modified Nanoparticles by Attenuating Protein Corona Adsorption
期刊论文
OAI收割
ACS NANO, 2024, 卷号: 18, 期号: 52, 页码: 35310-35324
作者:
Wang, Jie
;
Zhang, Zilong
;
Zhang, Zhuan
;
Zou, Zhiwen
;
Zhuo, Yan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/02/28
protein corona
ligand-modified nanoparticles
oral delivery
liver targeting
mucus