中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [17]
海洋研究所 [2]
采集方式
OAI收割 [19]
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期刊论文 [19]
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2021 [1]
2020 [1]
2017 [1]
2015 [1]
2014 [1]
2013 [2]
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学科主题
Pharmacolo... [3]
Chemistry [1]
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共19条,第1-10条
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Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel Arylaminoacetylhydrazone Derivatives Containing Carbazole Moiety
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3157-3170
作者:
Li Yingjun
;
Lin Ledi
;
Jin Kun
;
Gao Lixin
;
Sheng Li
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/11/04
protein tyrosine phosphatase 1B (PTP1B) inhibitor
carbazole
arylaminoacetylhydrazone
synthesis
molecular docking
3,6-二取代三唑并噻二唑衍生物的合成及其对细胞分裂周期25B磷酸酶和蛋白酪氨酸磷酸酶1B抑制活性评价
期刊论文
OAI收割
应用化学, 2020, 卷号: 37, 期号: 9, 页码: 994
作者:
李英俊
;
杨鸿境
;
曹欣
;
高立信
;
靳焜
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/24
triazolothiadiazole
benzimidazole
aryloxyacetic acid
cell division cycle 25B phosphatase inhibitor
protein tyrosine phosphatase 1B inhibitor
三唑并噻二唑
苯并咪唑
芳氧乙酸
细胞分裂周期25B磷酸酶抑制剂
蛋白酪氨酸磷酸酶1B抑制剂
Discovery of Bisindole as a Novel Scaffold for Protein Tyrosine Phosphatase 1B Inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2017, 卷号: 350, 期号: 1
作者:
Jing, Changcheng
;
Li, Ziyan
;
Jia, Kaili
;
Chen, Chen
;
Liu, Xiao
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Inhibitor
Mixed 3,3 '-bisindoles
Molecular docking
Protein tyrosine phosphatase 1B
Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 15, 页码: 4891-4898
作者:
Du, Yongli
;
Ling, Hao
;
Zhang, Meng
;
Shen, Jingkang
;
Li, Qunyi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Protein tyrosine phosphatase 1B inhibitor
N-(2,5-Diethoxy-phenyl)-methanesulfonamide
Type 2 diabetes mellitus
Insulin signaling
4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 14, 页码: 3670-3683
作者:
Zhi, Ying
;
Gao, Li-Xin
;
Jin, Yi
;
Tang, Chun-Lan
;
Li, Jing-Ya
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Protein tyrosine phosphatase 1B inhibitor
4-Quinolone-3-carboxylic acid
Bidentate ligand
Bioisostere
Insulin receptor signaling
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice
期刊论文
OAI收割
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:
Shi, Dayong
;
Guo, Shuju
;
Jiang, Bo
;
Guo, Chao
;
Wang, Tao
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2014/07/17
bromophenol
protein tyrosine phosphatase 1B inhibitor
db/db mouse model
anti-diabetes properties
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice
期刊论文
OAI收割
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:
Shi, Dayong
;
Guo, Shuju
;
Jiang, Bo
;
Guo, Chao
;
Wang, Tao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
bromophenol
protein tyrosine phosphatase 1B inhibitor
db/db mouse model
anti-diabetes properties
Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 23, 页码: 7237-7242
作者:
He, Hai-Bing
;
Gao, Li-Xin
;
Deng, Qi-Feng
;
Ma, Wei-Ping
;
Tang, Chun-Lan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
4,4-Dimethyl lithocholic acids
Protein tyrosine phosphatase 1B
Inhibitor
SAR
Diabetes
Natural products possessing protein tyrosine phosphatase 1B (PTP1B) inhibitory activity found in the last decades
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 10, 页码: 1217-1245
作者:
Jiang, Cheng-shi
;
Liang, Lin-fu
;
Guo, Yue-wei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
natural products
phytochemistry
protein tyrosine phosphatase 1B (PTP1B)
inhibitor
structure-activity relationship (SAR)
type 2 diabetes
obesity
Design, Synthesis, and Biological Evaluation of Bromophenol Derivatives as Protein Tyrosine Phosphatase 1B Inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2012, 卷号: 345, 期号: 6, 页码: 444-453
作者:
Jiang, Bo
;
Shi, Dayong
;
Cui, Yongchao
;
Guo, Shuju
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2013/09/24
Bromophenol
Protein tyrosine phosphatase 1B inhibitor
Structure-activity relationship
Type 2 diabetes mellitus