中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery and optimization of Menin-MLL inhibitors targeting acute myeloid leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 15
作者:
Xiao, Qitao
;
Wang, Yuxian
;
Shen, Zheyuan
;
Mo, Jun
;
Li, Cong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
MLL-R AML
Menin inhibitor
thieno[2
d ]pyrimidine
Machine learning
Towards sustainable potato production in China: Optimizing nitrogen and water management with 5R strategies
期刊论文
OAI收割
EUROPEAN JOURNAL OF AGRONOMY, 2026, 卷号: 175, 页码: 128021
作者:
Pan, Zhaolong
;
Jiang, Rong
;
Fan, Daijia
;
Song, Daping
;
Xie, Hanyou
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2026/03/16
Potato
4R
N management
Enhanced-efficiency fertilizers
Irrigation
Analysis of the coupling relationship and influencing factors between pollution reduction and carbon reduction and economy from the perspective of urban agglomeration
期刊论文
OAI收割
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY, 2026, 卷号: N/A
作者:
Chen, Xiaolong
;
Di, Qianbin
;
Liang, Chenlu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2026/04/16
Pollutant
Carbon reduction
Economy
Factors
Urban
Model
Q56
R11
O44
Integrating machine learning and numerical methods for enhanced landslide susceptibility and hazard mapping in the Bhotekoshi watershed, central Nepal
期刊论文
OAI收割
JOURNAL OF MOUNTAIN SCIENCE, 2026, 页码: 21
作者:
Gurung, Bishal
;
Chen, Ningsheng
;
Hu, Guisheng
;
Khadka, Nitesh
;
Sapkota, Liladhar
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2026/03/31
Disaster
Machine learning
Landslide runout modeling
r.avaflow
Koshi Basin
CSF1R inhibitor C19 for glioma immunotherapy enabled by brain-targeting liposomal delivery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 11
作者:
Song, Wen-qin
;
Wu, Yue-qian
;
Zhu, Quan-feng
;
Xia, Xing-ping
;
Wang, Rui
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
glioma immunotherapy
tumor-associated macrophages
CSF1R inhibitor
blood-brain barrier
brain-targeted delivery
Molecular basis for cross-activation of NPFF2R by a short PrRP-related peptide
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 11
作者:
Li, Xin
;
Li, Shuai
;
Shan, Hong
;
Yuan, Qing-ning
;
He, Xin-heng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
prolactin-releasing peptide
PrRPR
NPFF2R
ligand recognition
obesity therapy
PLN-L31A/I40A for the treatment of inherited heart disease caused by PLN-R14del mutations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 13
作者:
Chen, Zi-yang
;
Guo, Ren
;
Wang, Min
;
Ji, Si-jia
;
Zhang, Jing-wei
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
dilated cardiomyopathy
phospholamban
PLN-R14del
PLN-L31A/I40A
CRISPR-Cas9
human embryonic stem cell
Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 23
作者:
Zheng, Jiefang
;
Tian, Yaxin
;
Cheng, Jiaxin
;
Hu, Zhengtao
;
Zhang, Junchi
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
Antidepressants
Multimodal monoaminergic compounds
Triple monoamine reuptake inhibitors
5-HT 3A R antagonist
Aryl-spirocyclic diamine derivatives
Notoginsenoside R1 mitigates UVB-induced skin sunburn injury through modulation of
N
4
-acetylcytidine and autophagy
期刊论文
OAI收割
CHINESE MEDICINE, 2025, 卷号: 20, 期号: 1, 页码: 25
作者:
Liang, Shuyun
;
Liu, Xiaokang
;
Yang, Yuting
;
Zhang, Fangyuan
;
Sun, Xiaobo
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/01/29
Panax Notoginseng Saponins (PNS)
Notoginsenoside R1 (NGR1)
N
-acetyltransferase 10 (NAT10)
Ultraviolet B (UVB) Radiation
PI3K/AKT/mTOR Signaling Pathway
Autophagic Process
Selective recruitment of core rhizobacterial communities with distinct life-history strategies by two grass genera
期刊论文
OAI收割
JOURNAL OF PLANT ECOLOGY, 2025, 卷号: 18, 期号: 6, 页码: rtaf108
作者:
Wang, Yingcheng
;
Wang, Junbang
;
Wu, Chu
;
Zhou, Huakun
;
Zhang, Miao
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/12/19
core rhizobacteria
dominant grass
functional predictions
r/K-selection theory
Qinghai-Tibetan Plateau region